Oral antithrombotic use among myocardial infarction patients.

Ann Pharmacother

Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.

Published: January 2003

AI Article Synopsis

  • The study analyzed the use of oral antithrombotics in the Netherlands among myocardial infarction (MI) patients from 1988 to 1998.
  • The findings showed a significant increase in antithrombotic treatment from 54% in 1988 to 88.9% by 1998, with newer MI patients receiving treatment at higher rates than those from the late 1980s.
  • It concluded that many patients with a prior history of MI were not receiving recommended oral antithrombotic therapy, highlighting the need to evaluate their treatment appropriateness and potentially start therapy.

Article Abstract

Objective: To examine the use of oral antithrombotics (i.e., antiplatelet agents, oral anticoagulants) after myocardial infarction (MI) in the Netherlands from 1988 to 1998.

Methods: Retrospective follow-up of 3800 patients with MI, using data from the PHARMO Record Linkage System.

Results: From 1988 to 1998, oral antithrombotic treatment increased significantly from 54.0% to 88.9%. In 1998, only 75.8% of patients who experienced a MI in the late 1980s received oral antithrombotic treatment compared with 94.4% of those who experienced a recent MI.

Conclusions: Oral antithrombotics were considerably underused in patients with a past history of MI. Therefore, these patients should be reviewed for antithrombotic therapy to assess whether their failure to use oral antithrombotics was right or wrong, and whether treatment should be initiated if possible.

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Source
http://dx.doi.org/10.1345/aph.1C038DOI Listing

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