Objectives: This study was undertaken to determine whether choline ingestion improves physical and cognitive performance following exhaustive load carriage exercise.
Methods: In a double-blind crossover study, 13 men (28 +/- 2 years) underwent four test sessions: load carriage treadmill and no-load carriage test sessions after taking choline or placebo. Physical and cognitive performance batteries were administered at the end of the test sessions.
Results: Choline ingestion (50 mg/kg body weight) significantly (p < 0.05) increased plasma choline concentrations during the load and no-load carriage test sessions. However, plasma choline did not decrease during the placebo load carriage test session, an indication that load carriage does not deplete circulating choline. There were no differences in performance on physical tasks, and choline ingestion had no effect on reaction time, logical reasoning, vigilance, spatial memory, or working memory.
Conclusion: In healthy men, supplemental choline did not affect physical or cognitive performance after exhaustive physical activity.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Acute Alpha-Glycerylphosphorylcholine Supplementation Enhances Cognitive Performance in Healthy Men.
Nutrients
December 2024
Exercise and Performance Nutrition Laboratory, Department of Kinesiology, Lindenwood University, St. Charles, MO 63301, USA.
Background: Choline is an essential nutrient required for proper cell functioning. Due to its status as a precursor to acetylcholine, an important neurotransmitter connected to cognition and neuromuscular function, maintaining or enhancing choline levels is of interest. Supplementation with alpha-glycerylphosphorycholine (A-GPC) can maintain choline levels, but its ability to offer support towards cognition remains an area of ongoing research.
View Article and Find Full Text PDFSalcaprozate-based ionic liquids for GLP-1 gastric delivery: A mechanistic understanding of in vivo performance.
J Control Release
January 2025
Novo Nordisk A/S, Global Research Technologies, 2760 Måløv, Denmark.
Oral delivery of peptides requires formulations with high concentrations of permeation enhancer (PE) to promote absorption, and often necessitates fasting time between dosing and food ingestion. Improved formulations promoting a more rapid absorption would increase convenience of use but requires a faster onset of action. We have developed a salcaprozate-based ionic liquid (IL) formulation, namely choline salcaprozate (CHONAC), for oral delivery of a glucagon-like peptide-1 (GLP-1) analogue via gastric absorption.
View Article and Find Full Text PDFEffect of an acute session of intermittent exercise on trimethylamine N-oxide (TMAO) production following choline ingestion.
Metabolomics
October 2024
School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, LE11 3TU, UK.
Article Synopsis
- Trimethylamine N-oxide (TMAO) is linked to bad heart health and is produced by gut bacteria, but how exercise affects its production is unclear.
- The study looked at how a single session of intermittent exercise influences TMAO production from choline intake in young, healthy individuals.
- Results showed that TMAO levels increased similarly whether choline was taken after exercise or after resting, indicating exercise doesn't change gut bacteria's behavior regarding TMAO production.
Eating Egg-Rich Diets and Modeling the Addition of One Daily Egg Reduced Risk of Nutrient Inadequacy among United States Adolescents with and without Food Insecurity.
J Nutr
November 2024
Department of Nutrition Science, Purdue University, West Lafayette, IN, United States. Electronic address:
Background: Adolescents have the poorest dietary intake throughout their lifespan. Food insecurity worsens these nutritional risks. Eggs are a nutrient-dense strategy to increase nutrient quality.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!