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Libman-Sacks endocarditis is a rare cardiac manifestation of anti-phospholipid syndromes, in which non-infectious thrombotic vegetations are found on the heart valves. Most patients are asymptomatic whereas the risk of thromboembolism is considerable. Diagnostic work-up is based on questioning and clinical examination data looking for extracardiac signs, biological data and also on imaging, and, above all, echocardiography.

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Patent foramen ovale (PFO) is a risk factor for cryptogenetic stroke; its closure should be considered in selected patients. It is not always clear whether symptoms (presyncope, paresthesia) apparently due to paradoxical embolism are related with other cardiovascular disorders such as arrhythmias. Flecainide administration for post-PFO-closure supraventricular arrhythmias can unmask a latent undiagnosed Brugada syndrome.

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Bayés syndrome and acute cardioembolic ischemic stroke.

World J Clin Cases

March 2017

Adrià Arboix, Division of Cerebrovascular, Universitat de Barcelona, 08029 Barcelona, Spain.

Bayés syndrome is an under-recognized clinical condition characterized by advanced interatrial block. Bayés syndrome is a subclinical disease that manifests electrocardiographically as a prolonged wave duration > 120 ms with biphasic morphology ± in the inferior leads. The clinical relevance of Bayés syndrome lies in the fact that is a clear arrhythmological syndrome and has a strong association with supraventricular arrhythmias, particularly atypical atrial flutter and atrial fibrillation.

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Article Synopsis
  • - The study aimed to assess the prevalence of patent foramen ovale (PFO) in patients with ischemic stroke, given the inconsistent associations found in previous research regarding PFO and stroke types, especially cryptogenic strokes.
  • - Conducted as a multicenter, prospective survey, the SISIFO study analyzed 1,130 patients with acute ischemic stroke using various imaging techniques and tests to identify risk factors and confirm PFO presence through echocardiography.
  • - Findings revealed a PFO prevalence of 21.9% overall, with rates of 23.5% in cryptogenic strokes and 21.3% in known cause strokes, and factors such as younger age, hypertension, and specific stroke characteristics were linked to
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