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Aim: To determine optimal mode of transesophageal pacing for selection of appropriate antiarrhythmic therapy for prevention of attacks of atrial fibrillation and flutter in patients with ischemic heart disease.

Material And Methods: Two hundred eighteen patients with ischemic heart disease and attacks of atrial fibrillation or flutter. Selection of antiarrhythmic drugs was carried out with the use of competitive, rapid, salvos of ultra rapid, and slowly accelerating ultra rapid modes of pacing. Results. Most effective and reproducible method for induction of attacks of atrial flutter and fibrillation was slowly accelerating ultra rapid mode of pacing. Average duration of positive clinical effect of preventive antiarrhythmic therapy selected basing on the results of this mode in patients with ischemic heart disease was 3.1-/+0.3 years. Unfavorable prognostic sign decreasing preventive effect of antiarrhythmic therapy was left atrial dilatation.

Conclusion: Slowly accelerating mode of transesophageal pacing was most effective tool for selection of antiarrhythmic therapy aimed at prevention of attacks of atrial fibrillation and flutter in patients with ischemic heart disease.

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