Minocycline-ethylenediaminetetraacetate lock solution for the prevention of implantable port infections in children with cancer.

Clin Infect Dis

Division of Internal Medicine, Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas, M. D. Anderson Cancer Center, Houston, TX 77030, USA.

Published: January 2003

In this prospective cohort study, minocycline-ethylenediaminetetraacetate (M-EDTA) was used as a lock solution in indwelling ports inserted in 14 children with cancer. No port infections, thrombotic events, or other adverse events were observed, compared with 10 port infections that occurred in 48 control patients whose ports were flushed with heparin. M-EDTA is a promising lock solution in long-term catheters.

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Source
http://dx.doi.org/10.1086/344952DOI Listing

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