Purpose Of Review: The use of an endoprosthesis to maintain lumenal patency is a well-established concept used in a variety of surgical settings, including cardiovascular and gastrointestinal pathologies. However, the utility of self-retaining endoprosthetics and their application in prostatic pathology and benign prostatic hyperplasia is not as clear. This report reviews recent developments in the management of symptomatic benign prostatic hyperplasia, particularly the current role of intraprostatic stenting in the advent of other minimally invasive therapies such as laser prostatectomy.
Recent Findings: Over the past 5 years, urology has witnessed the proliferation of minimally invasive surgical therapies for benign prostatic hyperplasia. These interventions have enabled the urologist to treat a problem whose management was once limited to medical therapy, transurethral resection of the prostate, or open, relatively morbid surgery. The role of stents as an intermediary in cases of treatment failure, or as definitive therapy for benign prostatic hyperplasia and its associated problems is still not clear, when compared with newer, minimally invasive options. Current literature on stents is relatively sparse. However recent studies demonstrate that permanent and temporary prostatic urethral stenting are effective in relieving obstruction and urinary retention. Nevertheless larger controlled clinical studies are needed to demonstrate the real value of this intervention.
Summary: Prostatic stenting has a definite role in the management of benign prostatic hypertrophy, but stents must be used with caution because complications are still relatively common, and their true efficacy and utility in the urological setting has not been determined.
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http://dx.doi.org/10.1097/00042307-200301000-00009 | DOI Listing |
BJU Int
January 2025
Faculty of Social Sciences (Health Sciences), Prostate Cancer Research Center, Tampere University, Tampere, Finland.
Objective: To assess the association between prostate-specific antigen (PSA) density (PSAD) and prostate cancer mortality after a benign result on systematic transrectal ultrasonography (TRUS)-guided prostate biopsy.
Patients And Methods: This retrospective study used data from the Finnish Randomised Study of Screening for Prostate Cancer (FinRSPC) collected between 1996 and 2020. We identified men aged 55-71 years randomised to the screening arm with PSA ≥4.
Front Oncol
January 2025
Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Purpose: To develop novel nomograms for predicting prostate cancer (PCa) and clinically significant prostate cancer (csPCa) in patients with prostate-specific antigen (PSA) < 10 ng/ml and PI-RADS v2.1 score ≤ 3.
Methods: We retrospectively collected data from 327 men with PSA < 10 ng/ml and PI-RADS score ≤ 3 from June 2020 to June 2024 in our hospital.
Sci Rep
January 2025
Department of Urology Surgery, Guizhou Provincial People's Hospital, Guiyang, 550002, Guizhou Province, China.
The imbalance between estrogen and androgen may be an important mechanism of BPH, but the specific mechanism remains unclear. We used mixed sustained-release pellets made of testosterone and estradiol (T + E) to stimulate the establishment of a BPH rat model. Compared to the prostate hyperplasia rat model using only androgens, the new prostate hyperplasia rat model can be observed to have better macroscopic and pathological characteristics of prostate hyperplasia.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
Department of Urology, An-Nan Hospital, China Medical University, Tainan, Taiwan. Electronic address:
Phthalate exposure is linked to prostate enlargement through sex hormonal changes and oxidative stress. However, its role and action mechanism in prostate cancer remain unclear. This study examined two patient cohorts: 204 patients undergoing prostate biopsy (24 benign and 180 malignancies) and 85 with confirmed prostate cancer receiving robotic-assisted radical prostatectomy.
View Article and Find Full Text PDFJ Endourol
January 2025
Faculty of Medicine, Ain Shams University, Cairo, Egypt.
To evaluate the efficacy of preserving urethral mucosa around verumontanum in all directions and at the prostatic apex on antegrade ejaculation preservation and early postoperative continence in patients undergoing transurethral resection of the prostate (TURP). A randomized controlled trial was conducted in our tertiary center on patients scheduled for TURP. Patients were randomly allocated into two equal groups.
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