Objective: The aim of this study is to investigate the value of phosphate levels in serum and urine in patients with recurrent renal stone disease.
Materials And Methods: The patients (n:60) were divided into two groups as first-time stone disease (group 1) and recurrent renal stone disease (group 2). The demographical datas and their historical information were recorded and physical examination was done. The sera and urine for 24 hr were obtained from patients to measure electrolyte levels especially phosphorus. In addition, based on presenting serum phosphate levels, patients were divided into the hypophosphatemia group, less than 2.5 mg/dl; normophosphatemia group, between 2.5-5.2 mg/dl; and hyperphosphatemia group greater than 5.2 mg/dl.
Results: The mean age of study group was 45 (21-70) years. Thirty-six patients (60%) were in group 1 and 24 patients (40%) were in group 2. No statistically correlation was found between stone recurrence and phosphate levels both in serum and urine. There was only a statistical association of K levels in 24-hour urine samples between group 1 and 2.
Conclusion: There was no significant association between stone recurrence and initial phosphate levels in the serum or in urine. We do not propose to determine phosphate levels routinely in management of patients with stone disease.
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http://dx.doi.org/10.1080/003655902320783881 | DOI Listing |
Anal Chem
January 2025
Center for Advanced Analytical Science, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Sensing Materials and Devices, School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, P. R. China.
The screening of glycoprotein markers has become an integral part of the in vitro diagnosis of malignant tumors. Herein, an electrochemical method based on alkaline phosphatase (ALP)-mediated enzymatic silver deposition is reported for the highly sensitive detection of glycoprotein tumor markers, in which ALP enzymes are decorated to the glycan moieties of targets via the lectin-carbohydrate interactions. As glycoproteins are conjugated with multiple glycan chains, lectin-mediated labeling can result in the decoration of each target with multiple ALP enzymes.
View Article and Find Full Text PDFJ Thromb Haemost
January 2025
Dalla Lana School of Public Health, University of Toronto, Toronto, Canada; Office of the Vice-Principal of Research and Innovation, University of Toronto Mississauga, Mississauga, Canada. Electronic address:
Background: Whether to stop oral anticoagulants after a first unprovoked venous thromboembolism (VTE) is challenging, partially due to an intriguingly higher risk of VTE recurrence (rVTE) in men after therapy discontinuation. DNA methylation (DNAm) differences between men and women might underly this sex-biased rVTE risk difference.
Aim: To investigate sex-specific associations between DNAm at cytosine-phosphate-guanine (CpG) sites and rVTE.
Metab Eng
January 2025
Engineering Biology Research Center, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501, Japan; Graduate School of Science, Technology, and Innovation, Kobe University, 1-1 Rokkodai, Nada, Kobe, Hyogo 657-8501, Japan; Research Center for Sustainable Resource Science, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan. Electronic address:
Polyhydroxyalkanoate (PHA) is an attractive bio-degradable plastic alternative to petrochemical plastics. Photosynthetic cyanobacteria accumulate biomass by fixing atmospheric CO, making them promising hosts for sustainable PHA production. Conventional PHA production in cyanobacteria requires prolonged cultivation under nutrient limitation to accumulate cellular PHA.
View Article and Find Full Text PDFJ Environ Manage
January 2025
INRAE, Aix-Marseille Univ., UMR RECOVER, Aix-en-Provence, France.
Drought stress during the plant's growing season is a serious constraint to plant establishment in arid and semiarid Mediterranean ecosystems. Plant growth promoting rhizobacteria (PGPR) as environmentally friendly and innovative management approach can be used to produce seedlings better adapted to these environments. We tested native PGPR strains isolated from drought-tolerant tree and shrub species originating from two climatically contrasting regions: hot-dry (Dehloran) and milder Mediterranean climate (Ilam).
View Article and Find Full Text PDFSci Total Environ
January 2025
Department of Chemistry, Université de Sherbrooke, Sherbrooke, QC, Canada; Université de Sherbrooke Water Research Group (GREAUS), Université de Sherbrooke, Sherbrooke, QC, Canada. Electronic address:
In Canada studies on the presence of trace organic contaminants (TrOCs) such as pharmaceuticals, personal care products, pesticides and flame retardants in lakes have primarily focused on the water column at localized scales. To address this gap, the occurrence of 44 TrOCs, representative of various types of human activities, was investigated in surface sediments (0-2 cm) from 193 lakes across Canada. A total of 28 targeted TrOCs were detected, with 99.
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