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Bosutinib for the Treatment of CML-Using it Safely: a Podcast.

Target Oncol

January 2025

Division of Hematology and SCT, Georgia Cancer Centre, Augusta, GA, USA.

Bosutinib is a second-generation tyrosine kinase inhibitor (TKI) approved for use in patients with newly diagnosed Philadelphia chromosome (Ph)-positive chronic phase (CP) chronic myeloid leukemia (CML), as well as Ph-positive CP, accelerated phase, or blast phase (with chemotherapy) CML resistant or intolerant to prior therapy. Clinical trials have shown bosutinib is effective as first-line therapy for patients with CML as well as in later lines of therapy after prior TKI failure. Bosutinib has an established safety profile; however, as with all TKIs approved for the treatment of CML, there are adverse events (AEs) that require management.

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Optimal BMI cutoff for lean MASLD/MetALD and adverse hepatic outcomes in East-Asian populations.

Eur J Intern Med

January 2025

Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, South Korea; Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea; Institute for Innovation in Digital Healthcare, Yonsei University Health System, South Korea. Electronic address:

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Fortuitous discovery of a superior and posterior pancreaticoduodenal artery originating from the right branch of the hepatic artery during cadaver dissection.

Morphologie

January 2025

Department of Digestive Surgery, Amiens Picardy University Hospital, 1, rondpoint du Pr-Cabrol, 80054 Amiens, France; Simplifying Care for Complex Patients, UR-UPJV 7518 SSPC, Clinical Research Unit, University of Picardie Jules-Verne, Amiens, France.

Introduction: The duodeno-pancreatic region is a highly vascularized area. The superior and posterior pancreaticoduodenal artery is a vessel primarily originating from the gastroduodenal artery. It exhibits rare anatomical variations, such as its emergence from the right branch of the hepatic artery, which we fortuitously identified during a cadaver dissection.

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