Objective: To evaluate the safety and efficiency of ropivacaine and fentanyl for continuous epidural analgesia during delivery.

Methods: Altogether 98 full-term primigravidas with vertex presentation were selected for this study. Epidural catheter was placed during delivery with the cervical dilation of 3 cm, and the mixture of 0.2% ropivacaine and 2 microgram/ml fentanyl at the initial dose of 5 ml was given for continuous epidural analgesia. Drug infusion was discontinued when the second stage of delivery started. Another 98 primigravidas of similar conditions without analgesia served as the control group.

Results: Analgesic group showed obvious pain-relieving effect (P<0.001) during the delivery, in which the active phase was significantly shortened (P<0.05). No obvious adverse effect arose in the mother and fetuses from the administration of analgesia.

Conclusion: Continuous epidural analgesia by pumping ropivacaine and fentanyl is effective and convenient for pain relief during delivery, and can be beneficial to the smooth progress of delivery.

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