Neonatal infections represented the second cause of morbidity at the neonatalogy service of the Maternity Hospital of Befelatanana, and they were the first cause of the perinatal mortality (81%). This prospective study was carried out from May 1997 and December 1998 and had concerned neonatal infections suspicions among newborns. Its purpose was to identify problems with regard to the management of those newborns and to assess the impact of the prevention. Over 14,009 births, 1,877 neonates had infections recorded during the first week of life. Were noticed as main pathogen germs isolated: Escherichia coli, groups B, A, G, D Streptococci and Staphylococcus aureus. The authors conclude that screening and early treatment of materno-fetal infections constitute with asepsis, prevention basis of neonatal infections.
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Front Immunol
March 2025
Division of Malaria Research, Proteo-Science Center, Ehime University, Matsuyama, Japan.
Individuals residing in malaria-endemic regions with high disease transmission can develop semi-immunity within five years of age. Although understanding the target of the IgGs in this age group helps discover novel blood-stage vaccine candidates and serological markers, it has not been well elucidated due to limited accessibility to plasmodial antigens and samples. This study presents the first comprehensive analysis of antibody levels in plasma obtained from Burkinabe children (n=80, aged 0 to 5 years) to 1307 proteins expressed by the eukaryotic wheat germ cell-free system.
View Article and Find Full Text PDFFront Public Health
March 2025
Center for Indigenous Health, Johns Hopkins University, Baltimore, MD, United States.
Background: According to the National Center for Health Data, in 2017 American Indians in North Dakota experience the highest age-adjusted mortality rate in the United States. Data shows that the age-adjusted death rate for all North Dakotans has steadily declined since 1979. However, mortality remains high among American Indians in North Dakota.
View Article and Find Full Text PDFCureus
February 2025
Pediatric Anesthesiology, Hospital Infantil de México, Federico Gómez, Mexico City, MEX.
Giant encephalocele is a rare pediatric surgical entity that poses unique challenges. Few cases have been reported in the medical literature, and its cause is unknown. Factors that increase the likelihood of developing this pathology are radiation, infections, hyperinsulinemia, vitamin deficiencies related to neural tube closure defects, maternal smoking, alcohol, and anticonvulsants.
View Article and Find Full Text PDFNutrients
February 2025
Keough School of Global Affairs, University of Notre Dame, Notre Dame, IN 46556, USA.
Background: Iron deficiency anemia (IDA) is a significant global health problem affecting close to 2 billion people worldwide. The prevalence of IDA is higher among children younger than five years and women of reproductive age, indicating an intergenerational correlation between maternal and child anemia. This study aims to analyze the association between maternal and child anemia in The Gambia.
View Article and Find Full Text PDFInt J Mol Sci
March 2025
Division of Basic Science and Translational Research, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Differences in male (M) and female (F) neonates' premature birth outcomes and placental trophoblast inflammation have been observed but are unknown to occur within the fetal membrane trophoblast layer (chorion trophoblasts [CTC]). This study examined whether sex-based differences in gene expression and inflammatory marker expression can be observed in CTCs under control or infectious inflammatory conditions modeling preterm birth. CTCs from six different patient-derived fetal membrane samples (3M/3F) were cultured and divided into experimental (Lipopolysaccharide [LPS]) and control groups for 6, 12, or 24 h.
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