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Toxicological effects of the Curatella americana extract in embryo development of female pups from diabetic rats.

Reprod Biol

December 2023

Laboratory of System Physiology and Reproductive Toxicology, Institute of Biological and Health Sciences, Federal University of Mato Grosso (UFMT), Barra do Garças, Brazil. Electronic address:

Maternal diabetes can influence the development of offspring during fetal life and postnatally. Curatella americana is a plant used as a menstrual cycle regulator and to prevent diabetes. This study evaluates the effects of C.

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Effects of diabetes between generations on the pre-embryos of rats.

An Acad Bras Cienc

December 2022

Programa de Pós-Graduação em Tocoginecologia, Universidade Estadual Paulista (UNESP), Faculdade de Medicina de Botucatu, Laboratório de Pesquisa Experimental em Ginecologia e Obstetrícia, Distrito de Rubião Júnior, s/n, 18610-879 Botucatu, SP, Brazil.

Pregestational hyperglycemia cause adverse effects on mothers and their offspring. We aimed to evaluate the maternal hyperglycemia influence on pre-embryos from diabetic rats and on their generations (daughters and granddaughters). Diabetes was induced in Sprague-Dawley rats.

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Introduction: The conventional in vitro fertilization and the intracytoplasmic sperm microinjection are currently the established techniques for the treatment of infertility. In the last decade, however, the process of in vitro fertilization has suffered several changes in ovulation induction and oocyte retrieval (Ranoux 1990, ; ).The INVO procedure has been used to treat patients with different causes of infertility in many countries.

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Phytochemical and antidiabetic analysis of Curatella americana L. aqueous extract on the rat pregnancy.

J Ethnopharmacol

July 2022

Laboratory of System Physiology and Reproductive Toxicology, Institute of Biological and Health Sciences, Federal University of Mato Grosso, 78605-091, Barra do Garças, Mato Grosso State, Brazil. Electronic address:

Ethnopharmacological Relevance: Curatella americana L. is employed in popular medicine for treating diabetes. However, the understanding around its outcomes during pregnancy is unclear.

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A brief and personal history of 'what's in a name' in reproductive genetics.

Med Humanit

May 2020

Obstetrics & Gynecology, Western University, Schulich School of Medicine & Dentistry, London, ON, Canada, N6A 5C1

Although Juliet's claim, 'What's in a name? That which we call a rose by any other name would smell as sweet', may apply to family names, 'that which we call' embryos and procedures in reproductive genetics often smell sweet because the names were created to perfume not-so-sweet-smelling practices. Reproductive-genetic scientists and clinicians, including myself, have used perfumed names to make our research smell sweet for research ethics boards, research grant funders, government regulators, hospital administrators and the general public. The sweet-smelling names in reproductive genetics explored here include 'pre-embryo', preimplantation genetic 'diagnosis', 'normal' embryo, 'suitable' embryo, 'healthy' embryo, preimplantation genetic 'testing', 'non-invasive prenatal testing', 'donation', and most recently 'mitochondrial replacement therapy', a sweet-smelling name for germline nuclear transfer prohibited in antireproductive cloning legislation in most countries.

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