In the past, needle suspensions were considered a viable option to treat female stress urinary incontinence. There have been many modifications since the first needle suspension over 40 years ago. Despite these modifications, the long-term outcome data does not support the efficacy of needle suspension procedures, with only a 67% cure/dry rate at > 48 months. The long-term results are much more efficacious with the sling procedure (83%), as well as with retropubic suspensions (84%). Needle suspensions have historical significance, but because of the poor long-term results, they currently have a limited role in the management of stress urinary incontinence.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0094-0143(02)00073-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
First Report of Causing Fruit Rot on Fig in China.
Plant Dis
January 2025
Kashi, Xinjiang, China, China;
Fig (Ficus carica L.) holds economic significance in Atushi, Xinjiang, but as fig cultivation expands, disease prevalence has risen. In July 2024, approximately 22% of harvested fig (cv.
View Article and Find Full Text PDFFirst Report of Anthracnoseon on L. Caused by in China.
Plant Dis
January 2025
Guilin, Guangxi, China;
L. is a tropical fruit, cultivated in various provinces of China, such as Guangxi, Taiwan, and Yunnan. This fruit has good edible and medicinal value.
View Article and Find Full Text PDFPre-assembled nanospheres in mucoadhesive microneedle patch for sustained release of triamcinolone in the treatment of oral submucous fibrosis.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
August 2024
Xiangya Stomatological Hospital and Xiangya School of Stomatology, Central South University; Hunan Engineering Research Center for Oral Digital Intelligence and Personalized Medicine; Hunan 3D Printing Engineering Research Center of Oral Care; WANG Songling Academician Workstation for Oral-maxilofacial and Regenerative Medicine, Central South University, Changsha 410078.
Objectives: Drug-loaded mucoadhesive silk fibroin (SF) microneedle patch can overcome the limitations of low bioavailability and significant pain associated with traditional treatment methods, such as topical application or injection of triamcinolone for oral submucous fibrosis (OSF). However, these systems release the drug too quickly, failing to meet the clinical requirements. This study aims to construct a mucoadhesive SF microneedle patch pre-assembled with silk fibroin nanospheres (SFN) and explore its ability to sustain the release of triamcinolone in the treatment of OSF.
View Article and Find Full Text PDFFirst Report of Postharvest Fruit Rot on Passion Fruit () caused by in the U.S.A.
Plant Dis
January 2025
University of Florida Tropical Research and Education Center, Plant Pathology, 1615 SE 23rd Way, Homestead, Florida, United States, 33031-3314;
The commercial production of passion fruit is geographically limited (California, Florida, and Hawaii), but the development of cold-tolerant varieties could expand it beyond warm-climate states (Stafne et.al. 2023).
View Article and Find Full Text PDFHigh-Throughput Dissociation and Orthotopic Implantation of Breast Cancer Patient-Derived Xenografts.
J Vis Exp
December 2024
Division of Exercise Physiology, Department of Health Professions, West Virginia University School of Medicine; Cancer Institute, West Virginia University School of Medicine; 3Department of Microbiology, Immunology, and Cell Biology, West Virginia University School of Medicine;
Article Synopsis
- Patient-derived xenografts (PDXs) offer a valuable approach to study breast cancer (BC) by mimicking real tumor environments and systemic effects, which in vitro models cannot achieve.
- A new method for orthotopic implantation of BC PDXs in immunodeficient mice eliminates the need for anesthesia, is less invasive, and allows for faster and scalable tumor model development.
- The validation process of the tumors includes assessing receptor status, confirming morphology, and verifying genetic similarity to patient samples, facilitating robust research across different BC subtypes.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!