In 1910 Ernst Unger started kidney transplantation in Germany, when he tried to cure an uremic patient in Berlin by transplanting a monkey kidney. But it was not until 1963 that the urologists Brosig and Nagel - again in Berlin - began relevant clinical renal transplantation. In the late sixties the teams in Munich and Heidelberg took over the main initiative. In the seventies the method was widely accepted as therapy in chronic renal failure. But the quantitative development in both parts of Germany was very slow. In 1977 less than 100 transplantations were carried out in East Germany and less than 300 in the West. But then the numbers reached 2 015 in 1990 in the BRD and 343 in the DDR, resp. Unfortunately after the reunification there was no further increase, the numbers rather fluctuated between 2 000 and 2 300. While the former difference between East and West may well be explained by different forms of organisation, the situation after the reunification might be due to the emotional discussions on legislation and necessary structural alterations, the roots of which are disclosed.
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http://dx.doi.org/10.1055/s-2002-35766 | DOI Listing |
Transplant Proc
January 2025
Hepatobiliary Surgery and Liver Transplantation Unit, Cruces University Hospital, Bilbao, Spain; BioBizkaia Research Health Institute, Barakaldo, Bizkaia, Spain. Electronic address:
Polycystic liver disease (PLD) is a hereditary condition, and its symptoms are due to the growth of cysts. Liver transplantation (LT) is the only curative treatment. A retrospective single-center analysis was conducted on the 10 LTs performed for PLD between 2004 and 2023.
View Article and Find Full Text PDFZhong Nan Da Xue Xue Bao Yi Xue Ban
August 2024
Nursing Department, Third Xiangya Hospital, Central South University, Changsha 410013.
Objectives: Sleep quality in kidney transplant recipients is closely associated with symptoms of fatigue and depression. Although subjective assessment tools like the Pittsburgh Sleep Quality Index and the Richards-Campbell Sleep Questionnaire (RCSQ) are widely used to evaluate sleep quality, there is a lack of studies utilizing polysomnography for objective evaluation. This study aims to investigate the correlation between sleep quality, fatigue, and depression in kidney transplant recipients using both subjective and objective methods, providing scientific evidence for improving their quality of life.
View Article and Find Full Text PDFTransplant Cell Ther
January 2025
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Department of Pediatric Oncology and Hematology, Berlin, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Hematology and Oncology, University Children's Hospital, Eberhard Karls University Tuebingen, Tuebingen, Germany.
Background: Hematopoietic stem cell transplantation (HSCT) serves as a therapeutic intervention for various pediatric diseases. Acute and chronic graft-versus-host disease (GVHD) are decisive determinants for allogeneic HSCT success. The immunosuppressive agent, ciclosporin A, is most often used to prevent GVHD in pediatric patients, but is known to be nephrotoxic.
View Article and Find Full Text PDFJ Glob Antimicrob Resist
January 2025
Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy. Electronic address:
PLoS One
January 2025
Department of Kidney Transplantation, Nephropathy Hospital, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaan'xi, China.
Increasing evidence suggests that dysbiosis of gut microbiota exacerbates chronic kidney disease (CKD) progression. Curcumin (CUR) has been reported to alleviate renal fibrosis in animal models of CKD. However, the relationship between CUR and gut microbiome in CKD remains unclear.
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