There are described a number of 9 clinical cases with unilateral myelinated nerve fibers, associated with myopia or amblyopia. Four cases developed extended myelinated areas, anisometropia with increased values, accentuated amblyopia and macular changes. Patients underwent treatment for amblyopia through correction with spectacles lenses and the occlusion of the congenerous eye. The obtained functional results differentiated the casemix in two groups: with therapeutic failure, 4 cases, characterized by extended myelination, anisometropia with an average of over -10 diopters and macular changes. with therapeutic success, 5 cases, characterized by reduced myelination, anisometropia with an average of over -4 diopters and normal maculae. It has been found a significantly statistical difference between the two groups as regarding the value of the anisometropia. However, the macular aspect has been an important factor in order the therapeutic effect to succeed. This clinical syndrome is differentiated from the unilateral simple myopia with amblyopia and from the myelinated nerve fibers without myopia or amblyopia.
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