The authors report the case of a 13-year-old migrant girl with urinary tuberculosis, presenting with urinary tract infection, severe frequency and unexplained fever. Intravenous urography demonstrated a non-functioning left kidney and a small fibrotic bladder. Retrograde cystography revealed stage 4 right vesicoureteric reflux. The presence of the Koch bacillus was identified on urine culture. Medical treatment by Rifampicin and Isoniazid was instituted for 18 months. Surgical management, consisting of left nephroureterectomy, subtotal cystectomy with augmentation enterocystoplasty and resection of the pelvic part of the right ureter with ureterointestinal reimplantation, was performed. With a follow-up of 19 years, this patient has normal renal function and no urinary disorders. This case recalls the reality of urinary tuberculosis in children and confirms its insidious nature. The destructive course of urinary tuberculosis may require major urinary tract reconstruction, as in our case.
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Diagn Microbiol Infect Dis
December 2024
State Key Laboratory of Respiratory Disease, Guangzhou Key Laboratory of Tuberculosis Research, Department of Tuberculosis, Guangzhou Chest Hospital, Institute of Tuberculosis, Guangzhou Medical University, Guangdong 510095, PR China. Electronic address:
Background: The simultaneous amplification/testing for tuberculosis (SAT-TB) targets specific 16s rRNA for detecting Mycobacterium tuberculosis in real-time.
Objective: To evaluate SAT-TB's performance in detecting intestinal and urinary TB using stool and urine samples.
Methods: Stool (94) and urine samples (69) (From 2021 to 2022), were collected from pulmonary combined with suspected intestinal or urinary tuberculosis.
Int Urol Nephrol
December 2024
Department of Urology, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cui Ying, Lanzhou, 730030, Gansu Province, China.
Objective: To analyze and discuss the clinical characteristics and risk factors of bilateral renal tuberculosis.
Methods: A retrospective study was performed on 446 patients who were diagnosed with renal TB. Among these patients, 69 patients with bilateral renal TB were selected as the observation group, and 377 patients with unilateral renal TB served as the control group.
Noncoding RNA Res
April 2025
Department of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th Street, Miami, FL 33199, USA.
MicroRNAs (miRNAs) are classified as small, non-coding RNAs that play crucial roles in diverse biological processes, including cellular development, differentiation, growth, and metabolism. MiRNAs regulate gene expression by recognizing complementary sequences within messenger RNA (mRNA) molecules. Recent studies have revealed that miR-145-5p functions as a tumor suppressor in several cancers, including lung, liver, and breast cancers.
View Article and Find Full Text PDFEthiop J Health Sci
October 2024
Department of Pathology, Addis Ababa University, College of Health Sciences, Addis Ababa, Ethiopia.
Background: Tuberculosis (TB) remains the deadliest infectious disease globally, with the kidneys being the most frequently affected organ in the genitourinary system. Isolated prostate involvement by tuberculosis is rare and may mimic prostate cancer. This case report aims to highlight the diagnostic challenges and therapeutic responses associated with isolated prostate tuberculosis, particularly in the context of significantly elevated prostate-specific antigen (PSA) levels in a TB-endemic region.
View Article and Find Full Text PDFJ Surg Case Rep
January 2025
Department of Urology, North Middlesex University Hospital, Sterling Way, London N18 1QX, United Kingdom.
Genitourinary tuberculosis is the second most common form of extrapulmonary tuberculosis. We present the case of a male patient in his late 20s who presented to his general practitioner with symptoms of recurrent urinary tract infection (UTI). Upon investigation his estimated glomerular filtration rate was found to be 61 ml/min/1.
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