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Circulating levels of adiponectin and AdipoR expression in peripheral blood mononuclear cells are associated with lower respiratory tract Infection.
Front Immunol
January 2025
Department of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Objective: The role of adiponectin (APN) in regulating inflammation is well recognized in metabolic disease, but the dysregulation of APN in lower respiratory tract infection (LRTI) remains controversial. We aimed to measure APN and its signaling receptors, adiponectin receptor (AdipoR), in peripheral blood mononuclear cells (PBMCs) from LRTI patients to explore their potential roles in the LRTI process.
Methods: A total of 99 LRTI patients from the Second Xiangya Hospital of Central South University were categorized into acute (n=35) and non-acute (n=64), and non-severe (n=62) and severe (n=37) groups.
A cross-sectional study on the correlation between internal cerebral vein asymmetry and hemorrhagic transformation following endovascular thrombectomy.
Front Neurol
January 2025
Department of Neurology and Institute of Neurology of First Affiliated Hospital, Institute of Neuroscience, Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, Fuzhou, China.
Introduction: Hemorrhagic transformation (HT) is a severe complication in patients with acute ischemic stroke due to large vessel occlusion (AIS-LVO) after endovascular treatment (EVT). We hypothesize that asymmetry of the internal cerebral veins (ICVs) on baseline CT angiogram (CTA) may serve as an adjunctive predictor of HT.
Methods: We conducted a study on consecutive AIS-LVO patients from November 2020 to April 2022.
Clinical study of colorViz fusion image vascular grading based on multi-phase CTA reconstruction in acute ischemic stroke.
BMC Med Imaging
January 2025
Department of Intervention, The First Affiliated Hospital of China Medical University,No.155 The Nanjing North street, Heping District, Shenyang, Liaoning, 110000, P.R. China.
Objective: This study aimed to evaluate the diagnostic value of ColorViz fused images from multi-phase computed tomography angiography (mCTA) using GE Healthcare's FastStroke software for newly diagnosed cerebral infarctions in patients with acute ischemic stroke (AIS).
Methods: A total of 106 AIS patients with unilateral anterior circulation occlusion were prospectively enrolled. All patients underwent mCTA scans during the arterial peak phase, venous peak phase, and venous late phase.
Preoperative Hematocrit Is Not Associated With Stroke After Surgery for Acute Type A Aortic Dissection.
J Cardiothorac Vasc Anesth
January 2025
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA. Electronic address:
Objective: To determine the impact of hematocrit on adverse neurologic events after acute type A aortic dissection (ATAAD) repair under deep hypothermic circulatory arrest.
Design: Retrospective study of consecutive aortic surgeries from 2010 to 2021.
Setting: Single institution.
Increased circulatory Krebs cycle metabolites in sepsis is associated with increased interleukin-6 release and worse survival.
Shock
January 2025
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Objective: Recent studies have proposed that Krebs cycle metabolites may serve as potential biomarkers for prognosis in sepsis. However, whether these metabolites are associated with disease severity and can be applied to improve the effectiveness of current prognosis assessment in sepsis remains unclear and is explored in this study.
Methods: This prospective multicenter cohort study was conducted in medical intensive care units (ICUs).
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