Purpose: To evaluate several protocols for depiction of the urinary collecting system with multi-detector row computed tomographic (CT) urography.
Materials And Methods: Fifty-one patients with hematuria or a suspicious renal mass underwent CT urography, during which thinly collimated (1-mm) pyelographic phase scanning was performed 8-10 minutes after contrast medium administration. Patients were examined while prone only (n = 17) and while both prone and supine (n = 17) after a 250-mL infusion of normal saline. Each collecting system and ureter was divided into six segments that were assigned opacification scores. All acquisition techniques were compared, and the highest-scoring technique was compared with that in 17 patients who underwent conventional intravenous urography (IVU). Three reconstruction techniques (transverse, coronal, and maximal intensity projection) were also compared. Stratified analysis was performed with the paired two-tailed Student t test to compare opacification scores for both the acquisition techniques and display methods, both individually and in all possible combinations.
Results: CT urography with supplemental saline administration, performed with the patient prone or supine, significantly improved mean opacification scores in the distal ureters (right, P =.004; left, P =.006). With this technique, CT urography produced a mean opacification score that was not significantly different from that with IVU in 11 of 12 segments and was significantly better than that with IVU in one of 12 segments (lower left ureter). Mean opacification scores obtained with transverse or coronal displays were equal to or higher than those obtained with maximum intensity projection reconstructions in all segments.
Conclusion: CT urography with a multi-detector row scanner and supplemental infusion of normal saline reliably displays the opacified urinary collecting system.
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http://dx.doi.org/10.1148/radiol.2253011515 | DOI Listing |
JMIR Res Protoc
January 2025
Clinical Physiology Institute, Consiglio Nazionale delle Ricerche, Pisa, Italy.
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View Article and Find Full Text PDFJMIR Res Protoc
January 2025
Clinical Informatics and Health Outcomes Research Group, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Background: There are gaps in our understanding of the clinical characteristics and disease burden of the respiratory syncytial virus (RSV) among community-dwelling adults. This is in part due to a lack of routine testing at the point of care. More data would enhance our assessment of the need for an RSV vaccination program for adults in the United Kingdom.
View Article and Find Full Text PDFJAMA Psychiatry
January 2025
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Importance: Depressive symptoms are associated with cognitive decline in older individuals. Uncertainty about underlying mechanisms hampers diagnostic and therapeutic efforts. This large-scale study aimed to elucidate the association between depressive symptoms and amyloid pathology.
View Article and Find Full Text PDFLasers Med Sci
January 2025
Department of Endodontics, Faculty of Dentistry, Gülhane Faculty of Dentistry, University of Health Sciences, Ankara, Turkey.
Objective: This study aims to quantitatively compare the effects of standard needle irrigation (SNI), passive ultrasonic irrigation (PUI), EDDY, photon-initiated photoacoustic streaming (PIPS), and shock wave-enhanced emission photoacoustic streaming (SWEEPS) on the apical extrusion of irrigation solutions in teeth with severe canal curvature.
Materials And Methods: Seventy-five teeth with a single root and canal, and curvature angles ranging from 20° to 40°, were selected for this study. Root canal curvatures were measured from buccolingual and mesiodistal radiographs using ImageJ software (version 1.
Evolution
January 2025
Department of Biology, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.
To better understand the sources of biological diversity in nature, we need information on the mechanisms underlying population divergence. Biological systems with patterns of naturally occurring adaptive variation among populations can provide insight into the genetic architecture of diverging traits and the influence of genetic constraints on responses to selection. Using a system of reproductive character displacement in the North American mushroom-feeding fly Drosophila subquinaria, we assessed patterns of genetic (co)variance among a suite of chemical signaling traits and divergence in this pattern among populations.
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