Synthesis of chloroplast galactolipids in apicomplexan parasites.

Eukaryot Cell

Laboratoire de Physiologie Cellulaire Végétale, UMR 5019 CNRS-CEA-Université Joseph Fourier, Département Réponse et Dynamique Cellulaire, CEA-Grenoble, 38054 Grenoble Cedex 9, France.

Published: August 2002

Monogalactosyldiacylglycerol and digalactosyldiacylglycerol are major chloroplast lipids of algae and land plants and are synthesized within the plastid envelope. Here we report that in Toxoplasma gondii and Plasmodium falciparum lysates, radiolabeled UDP-galactose is incorporated into monogalactosylcerebrosides, monogalactosyldiacylglycerol, and digalactosyldiacylglycerol due to distinct enzymological activities. Furthermore, DGDG is immunologically detected in apicomplexans.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC117996PMC
http://dx.doi.org/10.1128/EC.1.4.653-656.2002DOI Listing

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