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Phthalate esters in dusts from different indoor and outdoor microenvironment and potential human health risk: A case study in Beijing.
Environ Res
December 2024
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing, 100012, China. Electronic address:
Phthalate esters (PAEs) are widely used plasticizers that can easily migrate from plastic products, thereby presenting potential health risks through exposure. While PAE concentrations in dust have received increasing attention, there is still a lack of comprehensive understanding regarding their environmental distribution, composition profiles, and associated human exposure risks in Beijing. This study investigated the presence of seven PAEs in 124 dust samples collected from eight indoor and four outdoor microenvironment types across the Beijing metropolitan area.
View Article and Find Full Text PDF[Disseminated histoplasmosis with skin manifestations in advanced HIV: Case report].
Rev Med Inst Mex Seguro Soc
March 2024
Instituto Mexicano del Seguro Social, Hospital General de Zona No. 33, Departamento de Anatomía Patológica. Monterrey, Nuevo León, México.
Background: Histoplasmosis is a systemic mycosis caused by the agent Histoplasma capsulatum. Its clinical manifestations depend on the inhaled fungal load and can vary from an asymptomatic infection (90%) to a disseminated disease, especially in HIV infections and a CD4 T lymphocyte count of less than 150 cells. Its initial symptoms are nonspecific, including fever, weight loss, dry cough, and chest pain.
View Article and Find Full Text PDFEffect of breathing phase number on the 4D robust optimization for pancreatic cancer intensity modulated proton therapy.
BMC Cancer
October 2024
Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China.
Article Synopsis
- This study addresses the issues caused by respiratory movements during proton therapy for pancreatic cancer, which can harm healthy tissues and decrease tumor control, aiming to enhance treatment effectiveness through improved planning methods.
- Researchers analyzed data from 15 pancreatic cancer patients, creating various proton therapy plans that incorporated different numbers of respiratory phases to evaluate the impact on plan quality and efficiency.
- Results showed that plans utilizing 4D optimization outperformed 3D plans, particularly in targeting the tumor adequately while minimizing risks to surrounding organs, with 6-phase strategies proving most effective in maintaining dose consistency.
Inhalable and bioactive lipid-nanomedicine based on bergapten for targeted acute lung injury therapy via orchestrating macrophage polarization.
Bioact Mater
January 2025
State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, 55 N, Neihuanxi Road, Guangzhou, 510006, Guangdong, China.
Article Synopsis
- Acute lung injury (ALI) and acute respiratory distress syndrome are serious conditions linked to an imbalance in macrophage polarization (M1/M2), with current treatments presenting limitations like side effects and poor delivery.
- Researchers developed a new inhalable nanomedicine called Ber-lipo, combining bergapten with DPPC liposomes, which demonstrated promising anti-inflammatory effects and maintained macrophage balance in preclinical tests.
- In a mouse model of ALI, Ber-lipo effectively targeted inflamed lungs, improved lung function and tissue integrity, alleviated symptoms, and suppressed key signaling pathways involved in the disease's progression.
Assessing the Anxiolytic and Relaxation Effects of Essential Oil in University Students: A Comparative Study of EEG, Physiological Measures, and Psychological Responses.
Front Psychol
July 2024
College of Forestry, Fujian Agriculture and Forestry University, Fuzhou, China.
Background: is a commercially important tree species in China, and it's also a common native tree in the forests of southern China. However, literature on the impact of essential oil (CCEO) on human psychophysiological activity is scarce. Hence, the primary objective of this study was to examine the effect of exposure to CCEO on the functioning of the human autonomic nervous system, electroencephalographic (EEG) activity, and emotional state.
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