Eye Movement Desensitization and Reprocessing (EMDR) is an integrative psychotherapy approach that has been consistently evaluated as efficacious in the treatment of posttraumatic stress disorder (PTSD). The information processing model that guides its clinical application posits that EMDR should be effective in treating other psychological disorders that have experiential contributors. Research is needed to assess such applications. This special issue features three case series in which EMDR was applied to the treatment of complex PTSD, phobias, and chronic pain, respectively. The authors discuss deficits in the research literature, provide preliminary data on EMDR treatment of these conditions, and offer descriptive guidelines for evaluation that are achievable by the practicing clinician. Two additional articles offer preliminary data on physiological and cognitive/affective concomitants of therapeutic change. It is argued that clinicians should play a greater role in the rigorous and extensive examination of psychological treatments in the context of the exigencies of clinical practice.
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http://dx.doi.org/10.1002/jclp.10104 | DOI Listing |
Int J Geriatr Psychiatry
January 2025
Precision Neuroscience & Neuromodulation Program, Gordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Background: Alzheimer's disease (AD) is characterized by impaired inhibitory circuitry and GABAergic dysfunction, which is associated with reduced fast brain oscillations in the gamma band (γ, 30-90 Hz) in several animal models. Investigating such activity in human patients could lead to the identification of novel biomarkers of diagnostic and prognostic value. The current study aimed to test a multimodal "Perturbation-based" transcranial Alternating Current Stimulation-Electroencephalography (tACS)-EEG protocol to detect how responses to tACS in AD patients correlate with patients' clinical phenotype.
View Article and Find Full Text PDFPilot Feasibility Stud
January 2025
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Arch Phys Med Rehabil
January 2025
H. Ben Taub Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, TX, USA; Brain Injury Research Center, TIRR Memorial Hermann, Houston, TX, USA.
Objective: To test the efficacy of a randomized control trial low-touch mobile health intervention designed to promote care partner self-awareness and self-care.
Design: This randomized controlled trial (RCT) included a baseline assessment of self-report surveys of health-related quality of life (HRQOL), care partner-specific outcomes, and the functional/mental status of the person with TBI, as well as a 6-month home monitoring period that included three daily questions about HRQOL, monthly assessments of 12 HRQOL domains, and the use of a Fitbit® to continuously monitor physical activity and sleep. HRQOL surveys were repeated at 3- and 6-months post-home monitoring.
Toxicology
January 2025
School of Public Health, Dali University, Dali, Yunnan, China; Institute of Preventive Medicine, Dali University, Dali, Yunnan, China. Electronic address:
N-methyladenosine (mA) modification and LncRNAs play crucial regulatory roles in various pathophysiological processes, yet roles of mA modification and the relationship between mA modification and LncRNAs in cadmium-induced oxidative damage of pancreatic β-cells have not been fully elucidated. In this study, mA agonist entacapone and inhibitor 3-deazadenosine were used to identify the effects of mA on cadmium-induced oxidative damage as well as LncRNA changes. Our results indicate that elevated levels of mA modification by entacapone can rescue the cell viability and attenuate the cell apoptosis, while the inhibition levels of mA modification can exacerbate the cell death.
View Article and Find Full Text PDFAddict Behav
January 2025
Department of Psychology, University of Manitoba, Manitoba, Canada; Department of Pediatrics, University of Manitoba, Manitoba, Canada; Children's Hospital Research Institute of Manitoba, Manitoba, Canada.
Substance use disorders (SUD) in mothers of young children can negatively impact the family unit and promote the intergenerational cycle of mental health disorders. This systematic review aims to: 1) provide an overview of substance use treatments for mothers of young children (from birth to 5 years old); 2) synthesize findings on maternal substance use and child/maternal mental health outcomes; and 3) identify key treatment components. Database searches in Medline, PsycINFO, PubMED, and PsycARTICLES were conducted on May 7th, 2024.
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