Dental diseases in subjects with beta-thalassemia major.

Community Dent Oral Epidemiol

Department of Restorative Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, PO Box 030, Irbid 22110, Jordan.

Published: December 2002

Objectives: The aim of this study was to determine whether beta-thalassemia major is associated with an increase in the severity of periodontal disease and dental caries.

Methods: A total of 61 thalassemia patients and 63 healthy controls (age range = 6-18 years) were examined for plaque deposits, gingivitis, periodontitis and dental caries using Silness and Löe plaque index (Pl.I), Löe and Silness gingival index (GI), probing pocket depth (PPD) and DMFT, respectively.

Results: There were no significant differences in Pl.I, GI and PPD scores between both thalassemia patients and healthy control groups (P > 0.05). Dental caries was significantly higher in thalassemia patients group (P < 0.0001) compared to the healthy controls.

Conclusion: Thalassemia is not associated with increased levels of gingivitis or periodontitis but is associated with higher dental caries experience.

Download full-text PDF

Source
http://dx.doi.org/10.1034/j.1600-0528.2002.00012.xDOI Listing

Publication Analysis

Top Keywords

thalassemia patients
12
dental caries
12
beta-thalassemia major
8
patients healthy
8
gingivitis periodontitis
8
dental
5
dental diseases
4
diseases subjects
4
subjects beta-thalassemia
4
major objectives
4

Similar Publications

Sickle cell disease (SCD) and thalassemia are the most common hereditary disorders encountered in Central India. Timely identification of these disorders is critical to reduction in severe clinical manifestations and for identifying disease burden. Present study reports spectrum of hemoglobinopathies among the referred anemia patients to single centre in central India.

View Article and Find Full Text PDF

Genotype-phenotype correlation and potential genetic risk in the compound heterozygosity for unstable hemoglobins (UHbs) and α-thalassemia were discussed. Capillary electrophoresis and gene sequencing helped to establish the diagnosis. Hematological analysis showed the following findings: MCV 80.

View Article and Find Full Text PDF

Background: Current guidelines for screening glucose dysregulation (GD) in patients with transfusion-dependent thalassemia (TDT) recommend an annual 2-hour oral glucose tolerance test (OGTT) starting at the age of 10 years.

Objective: Assessment of adherence to OGTT screening in patients with TDT.

Methods: A questionnaire was distributed to 18 Thalassemia Centers in 10 different countries, targeting factors influencing adherence to annual OGTT screening in specialized multidisciplinary pediatric and adult TDT units and identifying strategies to improve adherence to OGTT in TDT patients.

View Article and Find Full Text PDF

Introduction: Hematologic malignancies, originating from uncontrolled growth of hematopoietic and lymphoid tissues, constitute 6.5% of all cancers worldwide. Various risk factors including genetic disorders and single nucleotide polymorphisms play a role in the pathogenesis of hematologic malignancies.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!