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Article Abstract
Objective: To research effects of Radix Astragali total saponin combined with Radix Paeoniae Rubra glucosides (double glucosides of Qi-Shao, DGQS) on antiplatelet.
Methods: Antiplatelet effect of DGQS at three dosages (100 mg/kg, 200 mg/kg, 400 mg/kg) were studied. And levels of granule membrane protein 140 (GMP-140), TXA2 and PGI2 in rat plasma were determined.
Results: DGQS as whole could restrain platelet aggregation, decrease content of GMP-140, bring down level of TXA2/PGI2.
Conclusion: DGQS had apparent antiplatelet effect.
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