A long-term raising study was carried out on male F344/DuCrj rats with three low protein (Crude Protein (CP); 14.5, 11.5, 8.5%) and low energy (Digestible Energy (DE); 2.0 kcal/g) diets from 4 to 104 weeks of age. In rats fed the 8.5% CP diet, body weight and digestible crude protein (DCP) consumption at 10 weeks of age were lower (P < 0.05) but the body weight at 50 weeks of age was higher (P < 0.05) than in the other groups. In rats fed the 8.5% CP diet the crude fat digestibility was higher (P < 0.05), and the CP/nitrogen-corrected metabolizable energy (MEn) ratio was low. On the other hand, the mean survival time at 80 weeks of age was shorter in rats fed the 8.5% CP diet (P < 0.05).
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http://dx.doi.org/10.1538/expanim.51.485 | DOI Listing |
JACC Adv
February 2025
Department of Medicine (Division of Cardiology), University of Alberta, Edmonton, Alberta, Canada.
Background: Cardiac disease is the leading cause of maternal mortality in developed countries, and myocardial infarction (MI) is an important cause of pregnancy-associated morbidity and mortality. These infrequent, but very serious, events are not optimally described in the medical literature.
Objectives: This study describes a 15-year consecutive, retrospective cohort of confirmed pregnancy-associated MIs (PAMIs) identified in Alberta, Canada (2003-2017).
Mediterr J Rheumatol
December 2024
Centro Universitário São Camilo, São Paulo-SP, Brazil.
Background: Hyaluronic acid (HA) has been largely used in clinical practice for rheumatic diseases. However, the effects of oral HA on these diseases are poorly understood.
Aim: To review articles evaluating oral HA's effects on rheumatic patients.
Indian J Orthop
February 2025
Department of Orthopaedics, PARAS HMRI Hospital, Patna, Bihar 800014 India.
Introduction: Aseptic nonunion is prevalent in orthopedic practice, causing persistent pain and functional impairment. Humeral shaft fractures, accounting for 3-5% of all fractures, have nonunion rates of 2-33% in nonoperative and 5-10% in surgical management. This study, the largest case series on operative management of aseptic humeral shaft nonunion (AHSN), treated with plate osteosynthesis.
View Article and Find Full Text PDFAnatol J Cardiol
January 2025
Department of Physiology, Gazi University Faculty of Medicine, Ankara, Türkiye.
Background: A primary factor in the pathogenesis of aging is oxidative stress, with cardiac inflammation and fibrosis being contributed to by increased oxidative stress as organisms age. Oxidative stress enhances the cardiac fibrotic signaling pathway, with reactive oxygen species inducing cardiac fibrosis through increased expression of the profibrotic factor transforming growth factor-beta 1 (TGF-β1). Furthermore, Wnt/β-catenin signaling pathway is implicated in interstitial fibrosis, which is associated with TGF-β.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
January 2025
Department of Child Healthcare, Changsha City Maternal and Child Health Care Hospital, Chengnan East Road No.416, Yuhua District, Changsha, 410007, China.
Background: Birth weight is a critical indicator for assessing fetal development and newborn health status. This study aimed to examine both linear and nonlinear associations between maternal age and birth weight and their related adverse outcomes.
Methods: 15,923 delivery data from 2018 to 2021 for pregnant women from the Changsha Maternal and Child Health Care Hospital were reviewed by a retrospective study.
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