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[Paucisymptomatic and reversible myelinolysis after an anaphylactic shock]. | LitMetric

[Paucisymptomatic and reversible myelinolysis after an anaphylactic shock].

Rev Neurol (Paris)

Service de Neurologie, CHU Henri MONDOR, Créteil, France.

Published: November 2002

AI Article Synopsis

  • - Myelinolysis is a type of demyelination primarily affecting the central part of the pons, leading to symptoms like spastic tetraparesis and pseudobulbar paralysis.
  • - The case study involves a 58-year-old man who experienced pontine and extrapontine myelinolysis following an anaphylactic shock, despite not having low sodium levels (hyponatremia).
  • - The patient's condition improved over a few days, and MRI results normalized within three months, suggesting that mild myelinolysis can resolve on its own after a shock event.

Article Abstract

Myelinolysis is characterized by a non inflammatory demyelination, affecting the central portion of the pons. Clinical features usually reflect damage to the descending motor tracts and include spastic tetraparesis, pseudobulbar paralysis, and the locked-in syndrome. We describe the case of a 58-year-old man, who developed a pontine and extrapontine myelinolysis, without hyponatremia, after an anaphylactic shock. Follow up demonstrated improvement of the clinical signs after a few days and the normalization of the MRI three months later. Our observation shows that a paucisymptomatic and spontaneously regressive myelinolysis can be the consequence of a state of shock.

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