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The "best practices for farming" successfully contributed to decrease the antibiotic resistance gene abundances within dairy farms.
Front Vet Sci
January 2025
Laboratory of Microbial Ecology and Genomics, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Italy.
Introduction: Farms are significant hotspots for the dissemination of antibiotic-resistant bacteria and genes (ARGs) into the environment and directly to humans. The prevalence of ARGs on farms underscores the need for effective strategies to reduce their spread. This study aimed to evaluate the impact of a guideline on "best practices for farming" aimed at reducing the dissemination of antibiotic resistance.
View Article and Find Full Text PDFCombatting Salmonella: a focus on antimicrobial resistance and the need for effective vaccination.
BMC Infect Dis
January 2025
Division of Animal Biotechnology, Faculty of Veterinary Sciences & Animal Husbandry, SKUAST Kashmir, Shuhama, J&K, 190006, India.
Background: Salmonella infections represent a major global public health concern due to their widespread zoonotic transmission, antimicrobial resistance, and associated morbidity and mortality. This review aimed to summarize the zoonotic nature of Salmonella, the challenges posed by antimicrobial resistance, the global burden of infections, and the need for effective vaccination strategies to mitigate the rising threat of Salmonella.
Methods: A systematic review of literature was conducted using databases such as PubMed, Scopus, Web of Science, and Google Scholar.
Antimicrobial resistance (AMR) poses a significant global health challenge, prompting the World Health Organization (WHO) to stress the importance of monitoring antibiotic consumption and sales to address AMR effectively. This study protocol aims to optimize antibiotic stewardship and combat AMR in Central Asia through evidence-based practices and policies. The protocol includes objectives such as conducting systematic reviews of interventions to promote judicious antibiotic use, assessing antibiotic consumption trends, and investigating antibiotic overuse practices among healthcare providers.
View Article and Find Full Text PDFDiffuse Large B-Cell Lymphoma Presenting Primarily as a Cutaneous Leg Lesion: A Case Report and Literature Review.
Cureus
December 2024
Hematology and Medical Oncology, East Carolina University (ECU) Health Medical Center/Brody School of Medicine, Greenville, USA.
Primary cutaneous B-cell lymphoma (PCBCL) has three subtypes, among those, the leg type variant is the rarest with the highest rates of relapse and recurrence making it an intriguing focus for researchers. Nevertheless, prior to framing a diagnosis solely based on the lesion's location, it is prudent to reconsider whether it is genuinely a primary cutaneous B-cell lymphoma (PCBCL) or if it aligns more closely with the more prevalent lymphoma variants such as diffuse large B-cell lymphoma (DLBCL) with cutaneous involvement. We are reporting a case of an 85-year-old African American lady, who presented with unilateral left leg DLBCL with cutaneous involvement.
View Article and Find Full Text PDFVirulent and multidrug-resistant Aeromonas in aquatic environments of Kerala, India: potential risks to fish and humans.
Braz J Microbiol
January 2025
ICAR-Central Institute of Fisheries Technology (ICAR-CIFT), Willingdon Island, Cochin, Kerala, 682029, India.
Aeromonas inhabit diverse aquatic habitats and are recognized as both opportunistic and primary pathogens of fish and humans. This study delineates the biochemical and gyrB sequence-based molecular identification of 14 Aeromonas strains isolated from aquatic environments in Kerala, India, identifying them as A. dhakensis (50%), A.
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