[Association of ovarian juvenile granulosa cell tumor with Maffucci's syndrome].

Gynecol Obstet Fertil

Service de chirurgie carcinologique, institut national d'oncologie Sidi Mohamed Ben Abdellah, Rabat, Maroc.

Published: September 2002

AI Article Synopsis

  • The authors discuss a rare case of ovarian juvenile granulosa cell tumor linked to Maffucci's syndrome, which is characterized by enchondromatosis and hemangiomas without hereditary mesodermal dysplasia.
  • Sarcomatous changes in chondromas are common, but other tumor types, like the ovarian juvenile granulosa cell tumor, can also occur in young females with this syndrome.
  • The presence of sarcomatous changes in chondromas impacts the prognosis for patients with Maffucci's syndrome.

Article Abstract

The authors report a rare case of the ovarian juvenile granulosa cell tumor associated with Maffucci's syndrome (enchondromathosis + hemangiomas), no heriditary mesodermal dysplasia. Sarcomatous changes of chondromas are encountered most frequently; however other various typed neoplasma have been reported: ovarian juvenile granulosa cell tumor may occur not infrequently in female patients with Maffucci's syndrome in the first or second decades. Sarcomatous changes of choromas established prognosis of the Maffucci's syndrome.

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http://dx.doi.org/10.1016/s1297-9589(02)00416-2DOI Listing

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