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Association Between Circulating Fatty Acids and Blood Pressure: A Review.
Curr Nutr Rep
January 2025
Endocrinology and Nephrology Research Axis, CHU de Québec Research Center, CHU of Quebec-Laval University, CHUL - 2705, Boulevard. Laurier, Quebec, G1V 4G2, Canada.
Purpose Of Review: High blood pressure (BP) or hypertension (HTN) remains key risk factors for cardiovascular disease (CVD). Circulating fatty acids (FAs) in the blood can affect directly cardiovascular hemodynamics and serves as building blocks for endocrine mediators modifying inflammatory processes and vascular function. This review aims to describe optimal circulating FA profiles for BP to adjust dietary recommendations for HTN prevention.
View Article and Find Full Text PDFEffects of antihypertensives with and without IL-6 lowering properties on long-term blood pressure control: The prospective HELIUS cohort.
Int J Cardiol Cardiovasc Risk Prev
March 2025
Department of Public and Occupational Health, Amsterdam Public health Research Institute, Amsterdam university Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Article Synopsis
- Chronic inflammation, particularly the role of interleukin-6 (IL-6), is being explored as a target for improving hypertension treatment.
- In a study involving 1,510 participants over six years, it was found that calcium channel blockers (CCBs) with IL-6-lowering properties (specifically amlodipine and barnidipine) resulted in better blood pressure control compared to other CCBs.
- No significant differences were seen in blood pressure control among other antihypertensive classes or across different ethnic groups, indicating a need for further research into IL-6's impact on hypertension management.
Factors Affecting Outcomes of Percutaneous Transluminal Angioplasty for Central Vein Occlusive Disease in the University of the Philippines-Philippine General Hospital: A 10-Year Experience.
Acta Med Philipp
November 2024
Division of Thoracic, Cardiac and Vascular Surgery, Department of Surgery, College of Medicine and Philippine General Hospital, University of the Philippines Manila.
Objective: To describe the treatment outcomes of patients who underwent Percutaneous Transluminal Angioplasty (PTA) for Central Vein Occlusive Disease (CVOD) in end-stage kidney disease and determine the association between patient profile and treatment outcomes.
Methods: A single-institution, retrospective review of patients aged 18 and above with end-stage kidney disease who underwent PTA for CVOD in the University of the Philippines - Philippine General Hospital (UP-PGH) from January 1, 2013, to December 31, 2022, was performed. These patients' demographic and clinical profiles were evaluated using means, frequencies, and percentages.
Objective: ADHD is one of the most common neurodevelopmental disorders, seen in children and adolescents, and is often treated with various pharmacological agents, especially methylphenidate. There are differing opinions in the literature regarding the cardiovascular safety of long-term methylphenidate use. Studies suggest that the drug may increase the risk of hypertension, myocardial infarction, ventricular arrhythmia, sudden cardiac death, cardiomyopathy, heart failure (HF), pulmonary hypertension, and stroke.
View Article and Find Full Text PDFHazardous alcohol use and cardiometabolic risk among firefighters.
Alcohol Clin Exp Res (Hoboken)
January 2025
Neuromuscular and Occupational Performance Laboratory, Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, Texas, USA.
Article Synopsis
- Firefighters who misuse alcohol (high AUDIT-C scores) are at greater risk for various cardiometabolic issues, including higher cholesterol and blood pressure levels compared to those with low alcohol use.
- Mental health conditions like PTSD, depression, and anxiety may influence this risk, affecting how alcohol misuse relates to blood pressure and lipid levels.
- Overall, understanding these relationships is crucial since they could impact the firefighters' readiness for duty and overall health.
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