The ultrasonic Doppler technique was used to determine the effect of gravity on the linear velocity of blood flow in the main arterial vessels in the neck, brain and legs in 67 essentially normal human subjects of both sexes. The hemodynamic effect of gravity was neutralized by placing the subjects in the horizontal position; effects of the force of gravity were stimulated by active upright posture. It was shown that most commonly the arterial blood flow reacts to the orthostatic orientation by reducing the linear velocity, especially in the leg. These results indirectly witness that the hydrostatic pressure gradient on different levels of the arterial system in upright standing humans is not the only factor in reduction of the arterial blood linear velocity.

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