The intense battles preceding the recent promulgation of OSHA's Ergonomics Program Standard serve as a case study demonstrating the growing understanding that MSD causation, development, and exacerbation are the result of the combined contribution of (and possibly interaction between) a wide range of biomechanical and psychosocial stressors. The best designed studies, those that adequately measure both biomechanical and psychosocial exposures, strongly support this hypothesis. Work stress is one of the results of this stressor combination and is part of the physiological pathway to MSDs and a wide range of other occupational diseases. Prevention efforts geared to a single or single class of exposure may be only partly effective, ineffective, or even counter productive. The most effective control strategies are rooted in on-going, participatory ergonomics programs, incorporating a joint labor/management ergonomic team; this blueprint for intervention necessarily addresses the roots of both physical and psychosocial work stress experienced by workers.
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Metab Brain Dis
January 2025
Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Avenida Ipiranga, 2752, Porto Alegre, CEP 90610-000, RS, Brazil.
Phenylketonuria is a genetic disorder characterized by high phenylalanine levels, the main toxic metabolite of the disease. Hyperphenylalaninemia can cause neurological impairment. In order to avoid this symptomatology, patients typically follow a phenylalanine-free diet supplemented with a synthetic formula that provides essential amino acids, including L-carnitine.
View Article and Find Full Text PDFVet Res Commun
January 2025
Departamento de Microbiología e Inmunología, Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Ruta N 36 Km 601, Río Cuarto City, 5800, Córdoba, Argentina.
Post-weaning diarrhea (PWD) is a major concern for pig producers, as stress and early weaning increase susceptibility to enteropathogens like enterotoxigenic Escherichia coli (ETEC) and Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium).
View Article and Find Full Text PDFRes Involv Engagem
January 2025
Patient Researcher and PPI Lead, College of Health and Life Sciences, Aston University, Birmingham, UK.
Background: Patient and Public Involvement and Engagement (PPIE) has become an integral component of contemporary audiology research. It aims to capture diverse views and experiences, essential for evaluating the long-term impact of technological advancements and care models on individuals. Traditional inclusion methods, such as focus groups, may exclude individuals with additional needs or communication difficulties, necessitating the development of more inclusive approaches.
View Article and Find Full Text PDFMol Biol Rep
January 2025
Plant Protection and Bimolecular Diagnosis Department, Arid Lands Cultivation Research Institute, City of Scientific Research and Technological Applications, New Borg El-Arab 21934, Alexandria, Egypt.
Background: Heavy metal contamination, particularly from lead (Pb), poses a significant threat to plant agriculture worldwide, adversely affecting growth, physiological functions, and yield. Signalling molecules such as calcium and salicylic acid are known to mitigate various stresses in plants, prompting this study to explore their interaction with Pb stress in wheat.
Methods: A pot experiment was conducted in which wheat grains were primed with either distilled water, 5 mM calcium (Ca), or 0.
Sci Rep
January 2025
School of Resource, Environment and Safety Engineering, Hunan University of Science and Technology, Xiangtan, 411201, China.
In natural environments, most rocks possess internal fissures and are often exposed to diverse external loads arising from engineering activities and ground stress, among other factors. This study aims to explore the influence of different loading rates on the mechanical properties and acoustic emission (AE) characteristics of fissured rocks and to develop an intrinsic damage model. To achieve this, prefabricated fissured rock specimens that mimic natural rocks were prepared.
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