AI Article Synopsis
- Pulmonary vasospasm and hypertension can develop after surgery for congenital heart defects, which can sometimes be fatal despite standard treatments.
- Nitric oxide has been found to be effective in treating pulmonary hypertension that doesn't respond to other methods, but its use after certain heart procedures is not well documented.
- A case report illustrates a patient who showed rapid improvement in life-threatening pulmonary hypertension and desaturation after being treated with inhaled nitric oxide following a modified Blalock-Taussig shunt, suggesting the need for further research on its clinical application and potential preventive use.
Article Abstract
Pulmonary vasospasm and hypertension may occur after repair or palliation of congenital cardiac defects, and can be fatal in spite of conventional treatment. Nitric oxide has been shown to improve pulmonary hypertension unresponsive to conventional measures after a variety of repairs, but use has infrequently been reported after palliative systemic to pulmonary artery shunts. We report a case of pulmonary hypertension and life threatening desaturation after a modified Blalock-Taussig shunt that responded rapidly to inhaled nitric oxide. Clinical use, further study, and prospective analysis of prophylactic use of nitric oxide appear warranted.
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| http://dx.doi.org/10.1016/s0003-4975(02)03960-7 | DOI Listing |
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