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Carboplatin hypersensitivity presenting as coronary vasospasm - a case report. | LitMetric

Carboplatin hypersensitivity presenting as coronary vasospasm - a case report.

Cancer Chemother Pharmacol

Mary Potter Oncology Centre, Little Company of Mary Hospital, Groenkloof, Pretoria, Republic of South Africa.

Published: November 2002

A 68-year-old female patient with advanced ovarian carcinoma collapsed whilst receiving a carboplatin and cyclophosphamide infusion. This reaction was considered to fit with coronary vasospasm. Hypersensitivity to carboplatin is a rare but real complication of therapy and should be considered in patients presenting with hyperacute changes on ECG whilst receiving carboplatin therapy.

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Source
http://dx.doi.org/10.1007/s00280-002-0518-3DOI Listing

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