Objectives/hypothesis: The syndrome of inappropriate antidiuretic hormone or arginine vasopressin secretion (SIADH) is a disorder in which release of antidiuretic hormone is independent of plasma osmolarity, resulting in fluid retention and development of dilutional hyponatremia. The incidence of SIADH following neck dissection was found to be 18% to 30% in two separate reports. The incidence of SIADH in a cohort of patients who underwent neck dissection was prospectively studied.
Methods: Eighty-six patients were included in the study, along with a control group of 19 patients who underwent other neck procedures. Patient gender, age, physical condition (American Society of Anesthesiologists score), type of neck dissection, prior treatment, and smoking history were noted. Blood and urine osmolarity and sodium levels were sampled before surgery and during the first 24 hours after the surgery. These were recorded daily in cases with SIADH until the syndrome resolved.
Results: The incidence of SIADH was only 1.15% in patients before surgery. The syndrome developed in seven patients following neck dissection (8.14%) and in none of the patients in the control group. SIADH resolved within 72 hours at the latest. No association was found with patient gender, age, physical condition, or type or laterality of neck dissection. A statistically significant connection between the syndrome and history of smoking was noted (P <.05), and it was more commonly seen in patients with node-positive necks (P =.1231).
Conclusions: SIADH following neck dissection may be less common than formerly reported. Previous studies have presented contradicting data concerning the influence of tumor recurrence or prior radiation therapy on its incidence. Our results indicate no such association. A statistically significant connection between smoking and the syndrome was found. No clinical symptoms developed in the patients with SIADH, but it seems prudent to suggest limiting fluid intake in the first postoperative 24 hours for patients following neck dissection.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00005537-200211000-00020 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Craniofacial Pain Locations and Outcomes After Endoscopic Sinus Surgery for Unilateral Sphenoid Sinusitis: A Multi-Institutional Study.
Laryngoscope
January 2025
Department of Otolaryngology-Head and Neck Surgery, Henry Ford Health, Detroit, Michigan, U.S.A.
Introduction: Unilateral sphenoid sinus opacification on computed tomography is caused by a variety of pathologies including inflammatory and infectious sinusitis, benign and malignant tumors, and encephaloceles. The purpose of this study was to report craniofacial pain locations and outcomes in inflammatory unilateral sphenoid sinusitis (USS) patients who underwent endoscopic sinus surgery (ESS).
Methods: A multi-institutional retrospective cohort study was conducted on all adult patients who had ESS for USS from 2015 to 2022.
Lower Cranial Nerves in the Neck: An Anatomical Study.
Cureus
December 2024
Otorhinolaryngology Department, Unidade Local de Saúde de São João, Porto, PRT.
Objectives The aim of this anatomical study was to analyze distances and anatomical relations between the lower cranial nerves and important neck landmarks. Methods Anatomical study based on neck dissection in Thiel-embalmed cadavers. Anatomical relations and distances between the vagus (X), accessory (XI), and hypoglossal (XII) nerves and important neck landmarks were registered and compared.
View Article and Find Full Text PDFTransaxillary vs. Transsubclavian Gasless endoscopic thyroidectomy approaches for papillary thyroid cancer.
Sci Rep
January 2025
Department of Thyroid Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, 264099, China.
The use of transaxillary and transsubclavian approaches for endoscopic thyroidectomy has increased globally. However, studies examining the comparative outcomes of these procedures are scarce. In this study, we aimed to compare the safety and efficacy of thyroidectomy between the gasless endoscopic thyroidectomy transaxillary approach (GETTA) and gasless endoscopic thyroidectomy transsubclavian approach (GETTSA) in patients with papillary thyroid cancer (PTC).
View Article and Find Full Text PDFPedicle ossification following mandibular reconstruction using fibular free flap in a patient with osteoradionecrosis of the jaw: a case report.
J Korean Assoc Oral Maxillofac Surg
December 2024
Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Pedicle ossification is a rare but significant complication following mandibular reconstruction using a fibular free flap (FFF), a technique widely employed in maxillofacial surgery due to its reliable vascularized bone supply and low donor site morbidity. The FFF supports dental implantation and prosthetic rehabilitation, with its vascularized periosteum enhancing osteogenic potential. Despite these advantages, unexpected ossification of the flap's vascular pedicle may occur, potentially mimicking tumor recurrence and causing diagnostic uncertainty.
View Article and Find Full Text PDFPredictors, Trends, and Outcomes of Parathyroid Autotransplantation in Pediatric Total Thyroidectomy.
J Surg Res
December 2024
Division of Pediatric Surgery, Johns Hopkins All Children's Hospital, Saint Petersburg, Florida. Electronic address:
Introduction: Assess temporal utilization trends, identify predictors, and compare early postoperative outcomes of parathyroid autotransplantation (PTAT) in pediatric total thyroidectomy (TT) patients.
Methods: Patients <18 y undergoing TT between 2015 and 2021 were obtained from the National Surgical Quality Improvement Program-Pediatric database. Characteristics and outcomes were described and stratified by extent of node dissection.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!