Purpose: The aim of the study was to examine the effects of different lactate elevation protocols on the determination of the lactate minimum (Lac(min)) point.
Methods: Eight highly trained racing cyclists each completed four continuous ramp lactate minimum tests using the following blood lactate elevation protocols: 1) continuous ramp maximal aerobic power (RMP(max)) assessment, 2) 30-s maximal sprint, 3) 40-s maximal sprint, and 4) two 20-s maximal sprints separated by a 1-min recovery. Each blood lactate elevation protocol was followed by a 5-min active recovery leading into a continuous ramp test commencing at a power of 60% of RMP(max), using a 6 W x min ramp rate, lasting 15 min.
Results: Peak [La](b) values were significantly higher (P > 0.05) after the RMP(max) compared with all other protocols and higher in the 40-s versus 30-s sprint. However, by the start of Lac(min) ramp, [La](b) after the RMP(max) was no longer higher than the 40-s sprint, but Lac(min) [La](b) was similar for all protocols. This resulted in no differences in the total decline of [La](b) measured as a percentage from the highest to the lowest value. At Lac(min) point, there were no significant differences in power (P > 0.05), but heart rate was higher in the RMP versus 2 x 20 s and VO(2) was significantly higher after the 40 s compared with the 2 x 20 s protocol.
Conclusion: This study demonstrated that the determination of lactate minimum power in cycling is not dependent upon the lactate elevation protocol.
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http://dx.doi.org/10.1097/00005768-200211000-00009 | DOI Listing |
Sports Med Health Sci
March 2025
Sports and Exercise Physiology Laboratory, Department of Physiology, University of Calcutta, University Colleges of Sciences and Technology, 92 A.P.C. Road, Kolkata, 700009, India.
The present investigation examined the influence of age and pubertal transition on magnitude of muscle damage and inflammatory response following high intensity incremental treadmill running till volitional exhaustion in sixty-four sedentary prepubertal ( = 32) and postpubertal ( = 32) boys who were randomly recruited in the study. Muscle damage and inflammatory markers like creatine kinase (CK), lactate dehydrogenase (LDH), alanine aminotransferase (ALT), aspartate aminotranferase (AST), C-Reactive Protein (CRP) and Interleukin-6 (IL-6) were estimated before and after exercise. Serum CK, LDH, AST, ALT, CRP and IL-6 levels significantly increased after exercise in both the groups in comparison to respective pre-exercise values.
View Article and Find Full Text PDFFood Chem X
January 2025
Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, School of Basic Medical Science, Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025, PR China.
This study investigated the probiotic potential of fermented beverages derived from (). Three different beverages were prepared by fermenting water extract with A6-3 ( A6-3), A27-1 ( A27-1), or both for 48 h. The results demonstrated that bioactive compounds from promoted the growth of these two probiotics and preserved their viability for at least 28 days at 4 °C.
View Article and Find Full Text PDFWien Klin Wochenschr
January 2025
Department of Medicine III and Karl Landsteiner Institute for Metabolic Diseases and Nephrology, Klinik Hietzing, Vienna, Austria.
Aim/hypothesis: The main aim of the study was to identify point of care available laboratory and clinical predictors of 7‑day mortality in critically ill patients with a hyperglycemic crisis.
Methods: A retrospective study of 990 patients with the first hospitalization due to hyperglycemia was performed. Patients were classified as having diabetic ketoacidosis (DKA) or being in a hyperosmolar hyperglycemic state (HHS) according to the recommendations of the American Diabetes Association (ADA).
J Strength Cond Res
December 2024
Jayhawk Athletic Performance Laboratory, Wu Tsai Human Performance Alliance, University of Kansas, Lawrence, Kansas.
Eserhaut, DA, DeLeo, JM, and Fry, AC. Blood flow restricted resistance exercise in well-trained men: Salivary biomarker responses and oxygen saturation kinetics. J Strength Cond Res 38(12): e716-e726, 2024-Resistance exercise with continuous lower-limb blood flow restriction (BFR) may provide supplementary benefit to highly resistance-trained men.
View Article and Find Full Text PDFCureus
December 2024
Internal Medicine, Hospital Beatriz Ângelo, Lisboa, PRT.
Vitamin B12 deficiency is a potentially severe condition with clinical manifestations ranging from nonspecific symptoms, such as asthenia and glossitis, to severe hematological problems, including pancytopenia and megaloblastic anemia. One of the rare phenomena associated with this condition is pseudo-thrombotic microangiopathy (pseudo-TMA), which can mimic diseases such as thrombotic thrombocytopenic purpura (TTP), leading to possible misdiagnosis and inappropriate treatment. In this article, we present the case of a 62-year-old man with a history of intravenous drug use, untreated hepatitis C, smoking, and alcoholism.
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