The variability of El Niño/Southern Oscillation (ENSO) during the Holocene epoch, in particular on millennial timescales, is poorly understood. Palaeoclimate studies have documented ENSO variability for selected intervals in the Holocene, but most records are either too short or insufficiently resolved to investigate variability on millennial scales. Here we present a record of sedimentation in Laguna Pallcacocha, southern Ecuador, which is strongly influenced by ENSO variability, and covers the past 12,000 years continuously. We find that changes on a timescale of 2-8 years, which we attribute to warm ENSO events, become more frequent over the Holocene until about 1,200 years ago, and then decline towards the present. Periods of relatively high and low ENSO activity, alternating at a timescale of about 2,000 years, are superimposed on this long-term trend. We attribute the long-term trend to orbitally induced changes in insolation, and suggest internal ENSO dynamics as a possible cause of the millennial variability. However, the millennial oscillation will need to be confirmed in other ENSO proxy records.
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http://dx.doi.org/10.1038/nature01194 | DOI Listing |
Plants (Basel)
December 2024
Shaanxi Key Laboratory of Ecological Restoration in Northern Shaanxi Mining Area, College of Life Science, Yulin University, Yulin 719000, China.
The genus of L. are Tertiary-relict desert sand-fixing plants, which are an important forage and agricultural product, as well as an important source of medicinal and woody vegetable oil. In order to provide a theoretical basis for better protection and utilization of species in the L.
View Article and Find Full Text PDFInt J Equity Health
January 2025
Department of Health Management, School of Health Management, Southern Medical University, Guangzhou, 510515, China.
Objective: Perfect policy system support is the key to effective work, and policy evaluation can provide theoretical basis for policy revision. This study aims to quantitatively evaluate the two-way referral policy in China and thus improve the policy system of two-way referral.
Methods: This research focuses on 14 two-way referral policies published from 2007 to 2021.
Freshwater waterways, and species that depend on them, are threatened by urbanisation and the consequences of the urban stream syndrome. In south-east Queensland, Australia, little is known about the impacts of the urban stream syndrome on the platypus (), meaning that populations cannot be adequately managed by conservation practitioners. The aim of this study was to determine how habitat and environmental variables, related to the urban stream syndrome, influenced platypus distribution across this region.
View Article and Find Full Text PDFPeerJ
January 2025
College of Forestry, Guizhou University, Guiyang, Guizhou, China.
Masson pine ( Lamb.) and Chinese fir ( (Lamb.) Hook.
View Article and Find Full Text PDFStem Cell Res Ther
January 2025
Shenzhen Key Laboratory of Epigenetics and Precision Medicine for Cancers, Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, 518116, China.
Background: Patient-derived lung cancer organoids (PD-LCOs) demonstrate exceptional potential in preclinical testing and serve as a promising model for the multimodal management of lung cancer. However, certain lung cancer cells derived from patients exhibit limited capacity to generate organoids due to inter-tumor or intra-tumor variability. To overcome this limitation, we have created an in vitro system that employs mesenchymal stromal cells (MSCs) or fibroblasts to serve as a supportive scaffold for lung cancer cells that do not form organoids.
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