There is evidence to suggest that survival following surgery for colorectal cancer is improving. Audits undertaken in a single institution between 1974-1979 and 1991-1994 provide the opportunity to evaluate the extent to which earlier diagnosis and better surgery contribute to the improvement in survival. There was little evidence that patients were presenting at an earlier stage during the latter period. In contrast, more patients had a potentially curative resection. This analysis confirmed that, over this period, there has been a substantial improvement in survival following surgery for colorectal cancer; this improvement was largely due to better surgery rather than earlier presentation.
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http://dx.doi.org/10.1093/bmb/64.1.119 | DOI Listing |
JCO Precis Oncol
January 2025
Ge Zhang, MD, PhD, Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China, Henan Key Laboratory of Chronic Disease Prevention and Therapy & Intelligent Health Management, Zhengzhou, Henan, China, Tianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China; Shiqian Zhang, MD, PhD, Department of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Haonan Zhang, MD, PhD, Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Ruhao Wu, MD, PhD, Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; and Haoze Zheng, MD, PhD, Academy of Interdisciplinary Studies, Hong Kong University of Science and Technology, Hong Kong, China.
Dis Colon Rectum
October 2024
Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Background: Anal cancer disproportionately affects people living with HIV. The Department of Veterans Affairs is the largest single provider of healthcare to people living with HIV in the U.S.
View Article and Find Full Text PDFDis Colon Rectum
December 2024
Department of Colorectal Surgery, Cleveland Clinic, Ohio, United States.
Background: Deloyers technique addresses challenges in restoring bowel continuity following extended left hemicolectomies. Despite being first described in 1958, the technique remains underutilized, with limited data on long-term outcomes.
Objective: To evaluate the indications, surgical and functional outcomes of Deloyers technique and review existing literature.
Am J Gastroenterol
December 2024
Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Objectives: To prevent colorectal cancer (CRC), most patients with familial adenomatous polyposis (FAP) undergo (procto)colectomy with ileorectal anastomosis (IRA) or ileal pouch-anal anastomosis (IPAA). After surgery, these patients remain at risk of developing cancer in the remnant rectum or rectal cuff/pouch. We aimed to compare the long-term risk of cancer following IRA or IPAA in FAP.
View Article and Find Full Text PDFAm Surg
January 2025
Division of Hepatobiliary and Pancreas Surgery, Department of Surgery, The Jikei University School of Medicine, Minato-ku, Japan.
Background/aim: The aim of this study was to investigate the prognostic impact of the inflammatory burden index (IBI), a novel inflammation-based biomarker, in patients with colorectal liver metastases (CRLM) after hepatic resection.
Patients And Methods: One hundred fifty patients with CRLM who underwent hepatectomy were retrospectively analyzed. The IBI was defined as C-reactive protein × neutrophil count/lymphocyte count.
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