AI Article Synopsis
- Two new compounds (1 and 2) and three known compounds (3, 4, and 5) were identified from the roots of Broussonetia papyrifera.
- Spectroscopic methods were used to determine the structures of these compounds.
- Compounds 1, 3, 4, and 5 exhibited significant inhibitory effects on the PTP1B enzyme.
Article Abstract
Two new compounds, 8-(1,1-dimethylallyl)-5'-(3-methylbut-2-enyl)-3',4',5,7-tetrahydroxyflanvonol (1), 3'-(3-methylbut-2-enyl)-3',4',7-trihydroxyflavane (2) and three known compounds 3,3',4',5,7-pentahydroxyflavone (3), uralenol (4), broussochalcone A (5) were isolated from the roots of Broussonetia papyrifera, and their structures determined by spectroscopic methods. Compounds 1, 3, 4 and 5 significantly show the inhibitory activities against the PTP1B enzyme.
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| http://dx.doi.org/10.1016/s0960-894x(02)00757-6 | DOI Listing |
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