Severity: Warning
Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 143
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 143
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 209
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3098
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: Attempt to read property "Count" on bool
Filename: helpers/my_audit_helper.php
Line Number: 3100
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3100
Function: _error_handler
File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
The long-term degradation tissue response to poly-L-lactide (PLLA) screw was investigated for a minipig tibia fracture. As a bone-fracture model, three PLLA screws per animal were used to fix a tibia that had been subjected to a crank-shaped osteotomy. A total of 12 nine-month-old male minipigs were used. In time period from 1 month to 3 years, clinical, radiographic, and pathological studies were conducted. On macroscopic examination, no clear granuloma or fistula formation was noted for 3 years. On microscopic examination, no osteoclasts or giant cells were detected around the screws during the 3 years postoperatively. A substantial degradation of PLLA screw was observed between 2 and 3 years. At 3 years only slight residual breakdown products were found in macrophages. On electric microscopic examination, numerous degraded polymers were seen in a small number of macrophages around the screws. In this model, fixation of tibia fractures using PLLA screws was not associated with any side effects, and was safe and useful for up to 3 years.
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Source |
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http://dx.doi.org/10.1002/jbm.10388 | DOI Listing |
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