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Bone Tissue Engineering: From Biomaterials to Clinical Trials.
Adv Exp Med Biol
January 2025
Department of Stem Cells & Regenerative Medicine, Centre for Interdisciplinary Research, D Y Patil Education Society (Deemed to be University), Kolhapur, India.
Bone tissue engineering is a promising field that aims to rebuild the bone tissue using biomaterials, cells, and signaling molecules. Materials like natural and synthetic polymers, inorganic materials, and composite materials are used to create scaffolds that mimic the hierarchical microstructure of bone. Stem cells, particularly mesenchymal stem cells (MSCs), play a crucial role in bone tissue engineering by promoting tissue regeneration and modulating the immune response.
View Article and Find Full Text PDFAnalysis of scoliosis rod deformation after cutting with a surgical rod cutter.
Spine Deform
January 2025
Department of Orthopedic Surgery, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Purpose: Scoliosis is a complex multi-dimensional deformity of the spine that is common in children and adults. Of the various treatments for scoliosis, one is posterior spinal fusion with instrumentation. The rods typically used are composed of titanium or cobalt-chrome.
View Article and Find Full Text PDFWhat is the Learning Curve for Endoscopic Spine Surgery? A Comprehensive Systematic Review.
Spine J
January 2025
University of California Irvine, Department of Orthopaedic Surgery, 101 The City Drive South, Pavillion III, Building 29A, Orange, CA 92868. Electronic address:
Background Context: Endoscopic spine surgery (ESS) is rapidly emerging as a viable minimally invasive technique to successfully treat symptomatic degenerative spinal conditions. Widespread adoption has been limited in part due to the learning curve.
Purpose: To systematically review the learning curve for uniportal and biportal ESS and compare the two techniques.
Timing in orthopaedic surgery - Rethinking traditional myths with a critical perspective.
Injury
January 2025
Department of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany; Department of Trauma, Hand- and Reconstructive Surgery, University Hospital Giessen, Giessen, Germany. Electronic address:
Purpose: Standard operating procedures aim to achieve a standardized and assumedly high-quality therapy. However, in orthopaedic surgery, the aspect of temporal urgency is often based on surgical tradition and experience. At a time of evidence-based medicine, it is necessary to question these temporal guidelines.
View Article and Find Full Text PDFImpact of Antiplatelet Medication Continuation on Surgical Outcomes after Minimally Invasive Posterior Lumbar Decompression Surgery: Retrospective Cohort Study.
Global Spine J
January 2025
Department of Orthopedics, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.
Study Design: Retrospective cohort study.
Objectives: Spinal surgeons face a dilemma regarding the continuation or discontinuation of antiplatelet agents during the perioperative period. Guidelines recommend considering the balance between thrombotic and bleeding risks.
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