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Intravenous immunoglobulin ameliorates doxorubicin-induced intestinal mucositis by inhibiting the Syk/PI3K/Akt axis and ferroptosis.
Apoptosis
December 2024
Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, 610052, Chengdu, China.
Background: Chemotherapy-induced mucositis (CIM) significantly impacts quality of life and reduces survival in patients treated with specific chemotherapeutic agents. However, effective clinical treatments for CIM remain limited. Intravenous immunoglobulin (IVIg), a therapeutic derived from pooled human plasma, is widely used to treat inflammatory diseases.
View Article and Find Full Text PDFEnhanced Water Splitting Electrocatalysis with Heterointerfacial Cobalt Phosphide In Situ Supported on a Cellulose-Derived Carbon Aerogel.
Langmuir
December 2024
College of Textile Science and Engineering (International Institute of Silk), Zhejiang Sci-Tech University, Hangzhou 310018, China.
The active site density, intrinsic activity, and supporting substrate of cobalt phosphide catalysts are vital to their performance in alkaline water electrolysis. In this work, a CoP/CoP loaded on cellulose nanofiber-derived carbon aerogels (CP/CCAs) bifunctional electrocatalyst with a three-dimensional network and heterostructure is illustrated through sequential facile hydrothermal, freeze-drying, and phosphorylation processes. The three-dimensional network of carbon aerogels derived from cellulose nanofibers reveals a specific surface area of 183.
View Article and Find Full Text PDFProactive esophageal cooling during radiofrequency cardiac ablation: data update including applications in very high-power short duration ablation.
Expert Rev Med Devices
December 2024
NorthShore University Health System, Evanston, IL, USA.
Introduction: Proactive esophageal cooling reduces injury during radiofrequency (RF) ablation of the left atrium (LA) for the treatment of atrial fibrillation (AF). New catheters are capable of higher wattage settings up to 90 W (very high-power short duration, vHPSD) for 4s. Varying power and duration however does not eliminate the risk of thermal injury.
View Article and Find Full Text PDFMASLD Is Associated With an Increased Long-Term Risk of Atrial Fibrillation: An Updated Systematic Review and Meta-Analysis.
Liver Int
January 2025
Department of Medicine, University of Verona, Verona, Italy.
Background: Studies have reported an association between metabolic dysfunction-associated steatotic liver disease (MASLD) and an increased risk of developing atrial fibrillation (AF). However, the magnitude of the risk and whether this risk varies with the severity of MASLD remains uncertain.
Methods: In this systematic review and meta-analysis, we searched three large electronic databases using predefined keywords to identify cohort studies (published up to 30 September 2024) in which MASLD was diagnosed by liver biopsy, imaging methods, International Classification of Diseases (ICD) codes, or blood-based scores.
MedVantage: A Primary Care Model for Populations With High Social and Medical Needs.
Ochsner J
January 2024
The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA.
Despite the substantial expenditures on health care in the United States, persistent underperformance in health system metrics necessitates innovative approaches to address complex patient needs. The MedVantage Clinic in New Orleans, Louisiana, offers a regionally tailored, value-based primary care model targeting patients with high social and medical needs. This study provides an evaluation of the efficacy of the MedVantage Clinic in improving the cost of care and service utilization for this population.
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