Objectives: Many factors have been implicated in the etiopathogenesis of otitis media with effusion (OME). In this study, we investigated the role of allergy and the incidence of allergic rhinitis in patients with OME.
Patients And Methods: The study included 22 children (17 boys, 5 girls; mean age 7.8 years; range 2 to 12 years) with OME confirmed by findings of physical examination and tympanometry. Patients with high IgE levels and symptoms of allergic rhinitis were further investigated by skin prick tests and nasal smears. The results were compared with those of an age- and sex-matched control group (13 boys, 8 girls; mean age 7.8 years) with no symptoms of otolaryngological diseases.
Results: Symptoms of rhinitis, serum IgE levels, prick test and nasal smear findings suggested a diagnosis of allergic rhinitis in five children with OME (23%), and in one child (4.8%) in the control group. However, this difference did not reach significance (p>0.05).
Conclusion: Identification and appropriate treatment of allergic rhinitis in patients with OME may increase the success rate of OME treatment.
Download full-text PDF |
Source |
---|
Allergy Asthma Clin Immunol
January 2025
Allergy Research Unit, Kingston Health Sciences Center - KGH Site, Kingston, ON, Canada.
Respir Res
January 2025
Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China.
Background: Oxidative stress is key in inflammatory airway diseases. Heme oxygenase 1 (HMOX1) regulates oxidative stress, but its role in airway diseases needs exploration.
Methods: Differentially expressed genes (DEGs) between healthy nasal mucosa and chronic rhinosinusitis with nasal polyps (CRSwNP) were identified from Gene Expression Omnibus (GEO).
Ann Allergy Asthma Immunol
January 2025
Geisel School of Medicine, Dartmouth College, Department of Pediatric Nephrology; Geisel School of Medicine, Dartmouth College, Department of Integrative Health.
JAMA Pediatr
January 2025
Department of Pediatrics, Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina.
EClinicalMedicine
February 2025
Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University Marburg, Marburg, Germany.
Unlabelled: Non-communicable diseases (NCDs) characterised by type 2 inflammation, including asthma, allergic rhinitis, chronic rhinosinusitis with nasal polyps, atopic dermatitis, food allergies and eosinophilic esophagitis, are increasing in prevalence worldwide. Currently, there is a major paradigm shift in the management of these diseases, towards the concept of disease modification and the treatment goal remission, regardless of severity and age. Remission as a treatment goal in chronic inflammatory NCDs was first introduced in rheumatoid arthritis, and then adopted in other non-type 2 inflammatory diseases.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!