This study concerns the possible use of boundary layer (BL) approach for the analysis and evaluation of contaminant transport in groundwater due to contaminant penetration into the groundwater aquifer through a site of limited size. The contaminant penetration may occur through either the upper (surface) or lower (bedrock) boundary of the aquifer. Two general cases of contaminant penetration mechanisms are considered: (1) the contaminant is transferred through an interface between a contaminating and freshwater fluid phases, and (2) the contaminant arrives at groundwater by leakage and percolation. For the purpose of BL evaluation the contaminant plume is divided into three different sections: (1) the penetration section, (2) the extension-expansion section, and (3) the spearhead section. In each section a different BL method approach yields simple analytical expressions for the description of the contaminant plume migration and contaminant transport. Previous studies of the BL method can be directly applied to the evaluation of contaminant transport at the contaminant penetration section. The present study extends those studies and concerns the contaminant transport in the two other sections, which are located downstream of the penetration section. This study shows that the contaminant concentration profiles in sections 2 and 3 incorporate two BLs: (1) an inner BL adjacent to the aquifer bottom or surface boundary, and (2) an outer BL, which develops above or below the inner one. The method developed in the present study has been applied to practical issues concerning salinity penetration into groundwater in south central Kansas.
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http://dx.doi.org/10.1081/ese-120015461 | DOI Listing |
Nat Commun
December 2024
Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Penetrating orocutaneous or oropharyngeal fistulas (POFs), severe complications following unsuccessful oral or oropharyngeal reconstruction, remain complex clinical challenges due to lack of supportive tissue, contamination with saliva and chewed food, and dynamic oral environment. Here, we present a Janus hydrogel adhesive (JHA) with asymmetric functions on opposite sides fabricated via a facile surface enzyme-initiated polymerization (SEIP) approach, which self-entraps surface water and blood within an in-situ formed hydrogel layer (RL) to effectively bridge biological tissues with a supporting hydrogel (SL), achieving superior wet-adhesion and seamless wound plugging. The tough SL hydrogel interlocked with RL dissipates energy to withstand external mechanical stimuli from continuous oral motions like chewing and swallowing, thus reducing stress-induced damage.
View Article and Find Full Text PDFMol Cells
December 2024
Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea; Woo Choo Lee Institute for Precision Drug Development, Seoul 03722, Republic of Korea. Electronic address:
Plasma membrane proteins are crucial for signal transduction, trafficking, and cell-cell interactions, all of which are vital for cell survival. These proteins, including G-protein coupled receptors (GPCRs), ion channels, transporters, and receptors, are key drug targets due to their central role in receiving and amplifying cellular signals. However, the isolation and purification of plasma membrane proteins pose significant challenges because of their integration with phospholipid bilayers and the small fraction of these proteins present in the plasma membrane.
View Article and Find Full Text PDFIran J Parasitol
January 2024
Department of Microbiology, Arak University of Medical Sciences, Arak, Iran.
Background: We aimed to identity endosymbiont in -positive samples in natural and laboratory conditions.
Methods: Overall, 134 samples were collected from hospital environments. Microscopic and PCR test were used for detection of and The real-time PCR method was used to check the active presence of within under natural conditions from hospital samples and in co-culture laboratory conditions.
Food Microbiol
April 2025
School of Food Science and Engineering, South China University of Technology, Guangzhou, 510640, China; China-Singapore International Joint Research Institute, Guangzhou, China; Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health (111 Center), Guangzhou, China. Electronic address:
Photodynamic inactivation (PDI), a non-thermal sterilization method, has attracted considerable attention due to its broad-spectrum antimicrobial activity, environmental friendliness and cost-effectiveness. Curcumin (Cur), a food-grade photosensitizer, exhibits photodynamic antimicrobial activity based primarily on its efficiency in intracellular accumulation. However, Cur's low water solubility and the barriers presented by the outer membrane of Gram-negative bacteria challenge its ability to penetrate the cytoplasm.
View Article and Find Full Text PDFSci Total Environ
December 2024
International Center for Ecology, Meteorology, and Environment, School of Ecology and Applied Meteorology, Nanjing University of Information Science & Technology, Nanjing 210044, China. Electronic address:
Per- and polyfluoroalkyl substances (PFASs), a class of ubiquitous and emerging environmental pollutants, have garnered considerable attention due to the scarcity of knowledge regarding their atmospheric sources and the associated human health risks from aerosol exposure. This study investigated the spatial-temporal distribution and potential sources of PFASs in Nanjing city of eastern China by collecting 66 PM samples from industrial, urban, and rural areas between July 2022 and August 2023. Employing ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), 21 distinct PFASs were detected with concentrations ranging from 9.
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