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Automatic ovarian follicle detection using object detection models.
Sci Rep
December 2024
INRAE, CNRS, Université de Tours, PRC, Nouzilly, 37380, France.
Ovaries are of paramount importance in reproduction as they produce female gametes through a complex developmental process known as folliculogenesis. In the prospect of better understanding the mechanisms of folliculogenesis and of developing novel pharmacological approaches to control it, it is important to accurately and quantitatively assess the later stages of ovarian folliculogenesis (i.e.
View Article and Find Full Text PDFNight flight facilitates late breeding catch-up in a long-distance migratory seabird.
Sci Rep
December 2024
Department of Biology, University of Oxford, Mansfield Road, Oxford, OX1 3SZ, UK.
Long-distance migrants must optimise their timing of breeding to capitalise on resources at both breeding and over-wintering sites. In species with protracted breeding seasons, departing earlier on migration might be advantageous, but is constrained by the ongoing breeding attempt. Here we investigated how breeding timing affects migratory strategies in the Manx shearwater (Puffinus puffinus), a trans-hemispheric migratory seabird with large temporal variation in the onset of breeding.
View Article and Find Full Text PDFImpact of hyperkalaemia on renin-angiotensin-aldosterone (RAAS) inhibitor reduction or withdrawal following hospitalisation.
Clin Exp Med
December 2024
Department of Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Background: Inhibitors of the renin-angiotensin-aldosterone system (RAAS), such as ACE inhibitors (ACEi), angiotensin-II receptor blockers and mineralocorticoid receptor antagonists, reduce morbidity and mortality in hypertension, congestive heart failure and chronic kidney disease. However, their use can lead to hyperkalaemia. We examined the proportions of RAAS inhibitor (RAASi) reduction or withdrawal, across GFR strata, following hospitalisation and the effect on patient mortality.
View Article and Find Full Text PDFInsertion Behavior of Dialkylgermylene Ge(Flu) in Different E-X σ Bonds (E = Au, Si, Ge, Sn) and Its Relevance for Germanium Cluster Formation.
Inorg Chem
December 2024
Chemistry Department, University of Tübingen, Auf der Morgenstelle 18, 72076 Tübingen, Germany.
We present the insertion behavior of the alkyl-substituted germylene Ge(Flu) in different E-X σ bonds (E = Au, Si, Ge, Sn), first with the isolation of the germylgold complex (Flu)Ge(Cl)AuPPh. Afterward, the oxidative addition of GeCl to Ge(Flu) gives the digermane (Flu)Ge(Cl)GeCl, followed by a reductive elimination of GeCl and the formation of the oxidation product (Flu)GeCl. A comparable behavior is observed, with the homologues ECl (E = Si, Sn) stopping at different steps of the reaction.
View Article and Find Full Text PDFKinetics of elastic recovery in roll compaction.
Int J Pharm X
December 2024
Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Institute of Pharmaceutics and Biopharmaceutics, Universitaetsstrasse 1, 40225 Düsseldorf, Germany.
Elastic recovery ( ) has been investigated and discussed extensively in the field of tableting. However, until now only limited data is available regarding in roll compaction. Therefore, a previously established in-line measurement technique was rolled out to further investigate the kinetics of in roll compaction and the effects of specific compaction force ( ) and roll speed ( ).
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