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In traditional medical education, learners are mostly trained to diagnose and treat patients through supervised practice. Artificial Intelligence and simulation techniques can complement such an educational practice. In this paper, we present GLARE-Edu, an innovative system in which AI knowledge-based methodologies and simulation are exploited to train learners "how to act" on patients based on the evidence-based best practices provided by clinical practice guidelines.

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Association of serum vitamin D level and live birth rate in women undergoing frozen embryo transfer-a retrospective cohort study.

J Assist Reprod Genet

January 2025

Department of Obstetrics and Gynaecology, Li Ka Shing Faculty of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.

Purpose: To assess the association of serum vitamin D level and the live birth rate in women undergoing frozen embryo transfer (FET).

Methods: This is a retrospective cohort study involving 1489 infertile women who had frozen embryo transfer at two tertiary reproductive medicine centres from 2019 to 2021. Only the first frozen embryo transfer was included for women who had repeated transfers during the period.

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Background: The Clinical Dementia Rating scale Sum of Boxes (CDR-SB) measure is commonly used in specialist research settings and clinical trials. In clinical practice, shorter cognitive assessments, such as the Mini-Mental State Examination (MMSE), are commonly used. A targeted literature search identified existing MMSE - CDR-SB mappings; such as Balsis et al.

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Developing Topics.

Alzheimers Dement

December 2024

Alzheimer's Association, Chicago, IL, USA.

Background: The rapid development of blood-based biomarkers (BBMs) has improved Alzheimer's disease (AD) diagnostics with some tests now potentially suitable for clinical use. This aligns with the clinical availability of anti-Aβ immunotherapies for early symptomatic AD, where BBMs can help address the increasing need for more rapid and early diagnosis. Clinical practice guidelines (CPG) can help guide healthcare professionals in incorporating BBMs into their clinical practice.

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Dementia Care Practice.

Alzheimers Dement

December 2024

Johns Hopkins University School of Medicine, Baltimore, MD, USA.

The presentation of neuropsychiatric and sleep features in Lewy body dementia (LBD) are challenging to identify and manage. The US Based Diamond Lewy Neuropsychiatric Symptoms management guidelines provide expert consensus recommendations for the assessment and treatment of the neuropsychiatric features of LBD. These guidelines address the management of delusions, hallucinations, agitation and aggression, apathy, depression and anxiety.

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