Components for integrated poly(dimethylsiloxane) microfluidic systems.

Electrophoresis

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.

Published: October 2002

AI Article Synopsis

  • The review focuses on microfluidic systems made from poly(dimethylsiloxane) (PDMS), highlighting its desirable properties like elasticity, optical transparency, and low permeability to water.
  • Soft lithography is emphasized as an easy method for fabricating these systems, allowing for convenient integration of components and user interfaces compared to hard materials.
  • The text details various components used in PDMS microfluidics, including a passive chaotic mixer, pneumatic switches and valves, a magnetic filter, functional membranes, and optical elements.

Article Abstract

This review describes the design and fabrication of microfluidic systems in poly(dimethylsiloxane) (PDMS). PDMS is a soft polymer with attractive physical and chemical properties: elasticity, optical transparency, flexible surface chemistry, low permeability to water, and low electrical conductivity. Soft lithography makes fabrication of microfluidic systems in PDMS particularly easy. Integration of components, and interfacing of devices with the user, is also convenient and simpler in PDMS than in systems made in hard materials. Fabrication of both single and multilayer microfluidic systems is straightforward in PDMS. Several components are described in detail: a passive chaotic mixer, pneumatically actuated switches and valves, a magnetic filter, functional membranes, and optical components.

Download full-text PDF

Source
http://dx.doi.org/10.1002/1522-2683(200210)23:20<3461::AID-ELPS3461>3.0.CO;2-8DOI Listing

Publication Analysis

Top Keywords

microfluidic systems
16
fabrication microfluidic
8
systems
5
pdms
5
components
4
components integrated
4
integrated polydimethylsiloxane
4
microfluidic
4
polydimethylsiloxane microfluidic
4
systems review
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!