This article describes how the American Psychiatric Nurses Association (APNA) responded to the September 11 tragedy, as an organization. Also included are anecdotes from APNA members who participated individually in the aftermath of this tragedy. Because such a traumatic event can result in psychiatric disorders, a brief synopsis of these disorders is included. The economic effects of emotional difficulties for our nation are explored, especially those related to the most serious disorder resulting from such a traumatic event, Post Traumatic Stress Disorder. Strategies that APNA is focusing on for the future, as a result of this tragedy, are presented.
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Characterizing features affecting local ancestry inference performance in admixed populations.
Am J Hum Genet
December 2024
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; The Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA. Electronic address:
In recent years, significant efforts have been made to improve methods for genomic studies of admixed populations using local ancestry inference (LAI). Accurate LAI is crucial to ensure that downstream analyses accurately reflect the genetic ancestry of research participants. Here, we test analytic strategies for LAI to provide guidelines for optimal accuracy, focusing on admixed populations reflective of Latin America's primary continental ancestries-African (AFR), Amerindigenous (AMR), and European (EUR).
View Article and Find Full Text PDFHealthcare professionals face ethical challenges in managing care for neurodevelopmental disorders: a qualitative study in Lebanon.
BMJ Open
January 2025
Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.
Objectives: This study aimed to explore the ethical challenges faced by healthcare professionals (HCPs) in managing children and adolescents with neurodevelopmental disorders (NDDs) in Lebanon. The primary research question addressed how HCPs navigate ethical dilemmas related to patient autonomy, surrogate decision-making and communication in the context of severe cognitive impairments.
Design: Qualitative, cross-sectional study using semi-structured interviews.
Provision of Mental and Behavioral Health Supports and Services by Pharmacists in Washington State.
Community Ment Health J
January 2025
Department of Pharmacy, University of Washington School of Pharmacy, 1959 NE Pacific Street, Box 357630, Seattle, WA, 98195, USA.
Pharmacists are highly accessible healthcare professionals with presence in communities, hospitals, and clinics. They are well positioned to expand their roles in supporting individuals with mental health challenges. A cross-sectional study was conducted to identify trends in how pharmacists assess, monitor, identify, and care for patients with mental health challenges.
View Article and Find Full Text PDFBasic Science and Pathogenesis.
Alzheimers Dement
December 2024
Departments of Neurology, Psychiatry, and Epidemiology, Gertrude H. Sergievsky Center, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Background: Cardio and cerebrovascular risk factors (CVRFs) increase the risk of cerebrovascular disease and clinical Alzheimer's Disease (AD), and over 70% of the patients with AD coincident cerebrovascular pathology. We previously found that FMNL2 interacts with a burden score of hypertension, diabetes, heart disease, and body mass index (BMI) by altering the normal astroglial-vascular mechanisms that underly amyloid clearance. Stroke, defined by history of a clinical stroke or brain imaging, is a moderately robust risk factor for AD and dementia.
View Article and Find Full Text PDFBasic Science and Pathogenesis.
Alzheimers Dement
December 2024
Department of Population and Quantitative Health Sciences, Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.
Background: Recent advances in Alzheimer's Disease (AD) research have emphasized the importance of recruiting from diverse populations. Notably, African-descent individuals have an almost doubled risk of developing AD compared to European-descent individuals. Transcriptome-wide association studies (TWAS) have advanced the analysis of non-coding variants by integrating gene expression with GWAS data.
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