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Lymphomatoid Papulosis With T-cell Receptor-Gamma Delta Expression: A Clinicopathologic Case-series of 26 Patients of an Underrecognized Immunophenotypic Variant of Lymphomatoid Papulosis.
Am J Surg Pathol
May 2024
Department of Pathology.
Article Synopsis
- Lymphomatoid papulosis (LyP) can present in various ways and may be misdiagnosed as aggressive skin lymphomas, especially those involving γδ T-cells.
- A study analyzed 26 cases of LyP with γδ T-cell expression, noting that most patients were treated with topical steroids or had no treatment.
- The findings highlighted significant differences in how LyP presents, underlining the importance of recognizing specific clinical features and markers to avoid misdiagnosis.
MRI ischemic and hemorrhagic lesions in arterial and venous territories characterize central nervous system intravascular lymphoma in dogs.
Vet Radiol Ultrasound
March 2023
Diagnostic Imaging Department (Mattei, Specchi) and Neurology Department (Biserni), Ospedale Veterinario "I Portoni Rossi", Anicura Italy, Zola Predosa, Italy.
Article Synopsis
- A study analyzed MRI images and histopathology from 12 dogs with confirmed IVL, revealing specific brain and spinal cord lesions characterized by hyperintensities and changes indicative of vascular issues.
- The findings linked MRI features, like susceptibility artifacts and areas of infarction, to the unique blood vessel-targeting nature of IVL, highlighting ischemic and hemorrhagic influences caused by neoplastic infiltration in the affected areas.
Coexistence of gastric and pulmonary MALT lymphoma and a clonally related, disseminated large B cell lymphoma with conspicuous angiotropism.
Ann Hematol
June 2022
Department of Hematology, St. Mary's Hospital, 422, Tsubuku-honmachi, Kurume, Fukuoka, 830-8543, Japan.
The Cellular Choreography of Osteoblast Angiotropism in Bone Development and Homeostasis.
Int J Mol Sci
July 2021
Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham B15 2TT, UK.
Interaction between endothelial cells and osteoblasts is essential for bone development and homeostasis. This process is mediated in large part by osteoblast angiotropism, the migration of osteoblasts alongside blood vessels, which is crucial for the homing of osteoblasts to sites of bone formation during embryogenesis and in mature bones during remodeling and repair. Specialized bone endothelial cells that form "type H" capillaries have emerged as key interaction partners of osteoblasts, regulating osteoblast differentiation and maturation and ensuring their migration towards newly forming trabecular bone areas.
View Article and Find Full Text PDFTo elucidate the histopathological characteristics and immunophenotypes of canine transmural "mass-forming" gastrointestinal lymphomas and plasmacytomas, 83 surgically resected biopsy samples were examined. All lymphomas and plasmacytomas were located in the small or large intestine except for 1 plasmacytoma which was in the stomach. According to the World Health Organization (WHO) classification, B-cell neoplasms (17 cases) included lymphoplasmacytic lymphoma (6/17), plasmacytoma (5/17), follicular lymphoma (3/17), and diffuse large B-cell lymphoma (3/17).
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