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Impact of eggshell membrane on metabolism and cell adhesion in oxidatively stressed canine chondrocytes.
Front Vet Sci
January 2025
Centre of Experimental and Clinical Regenerative Medicine, Small Animal Clinic, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovakia.
Eggshell membrane (ESM) is a rich source of bioactive compounds, including proteins, peptides, and antioxidants, contributing to its potential therapeutic benefits. These natural antioxidants might help neutralize reactive oxygen species (ROS) and modulate inflammatory responses, which are often linked with chondrocyte damage in osteoarthritis. In this study, we investigated the functional effects of ESM proteins on HO-induced oxidative stress in a neonatal canine chondrocytes.
View Article and Find Full Text PDFComparison of transcutaneous bilirubin under patch-covered skin with total serum bilirubin in neonates undergoing phototherapy.
J Trop Pediatr
December 2024
Department of Neonatology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand 249203, India.
Transcutaneous bilirubinometry (TcB) is a recognized tool to monitor neonatal hyperbilirubinemia, demonstrating a high correlation with total serum bilirubin (TSB) before phototherapy. However, once phototherapy is started, TcB may become unreliable. To evaluate the correlation and agreement of TcB measured under variously patched skin at different sites (a coin over the sternum, eye shield over the forehead, and diaper area at the back) with TSB.
View Article and Find Full Text PDFImpact of COVID-19 pandemic measures on hospitalizations and epidemiological patterns of twelve respiratory pathogens in children with acute respiratory infections in southern China.
BMC Infect Dis
January 2025
Department of Respiratory, Shenzhen Children's Hospital, Shenzhen, 518038, China.
Objectives: To investigate the impact of COVID-19 pandemic measures on hospitalizations and the alterations and persistence of the epidemiological patterns of 12 common respiratory pathogens in children during the COVID-19 pandemic and after the cessation of the "zero-COVID-19" policy in southern China.
Methods: Respiratory specimens were collected from hospitalized children with acute respiratory infections at Shenzhen Children's Hospital from January 2020 to June 2024. Twelve common respiratory pathogens were detected using multiplex PCR.
Objectives: Kangaroo mother care (KMC) is high impact for survival of low birth weight neonates, but there are few rigorous evaluations of duration required for impact. We conducted a scoping review of KMC duration measurement methods and assessed their validation.
Design: Scoping review in accordance with Joanna Briggs Institute guidance for conducting scoping review.
Short-term modification of breathprint by Elexacaftor/Tezacaftor/Ivacaftor in a paediatric cohort.
J Cyst Fibros
January 2025
INSERM U1151, Institut Necker Enfants Malades, Paris, France; Hôpital Necker Enfants Malades, Centre de Référence Maladies Rares Mucoviscidose et Maladies apparentées, Paris, France; Université Paris-Cité, Paris, France; European Reference Network-Lung. Frankfurt, Germany. Electronic address:
Background: The triple combination Elexacaftor/Tezacaftor/Ivacaftor (ETI) translates into major respiratory improvements in adults; yet current clinical endpoints may prove insufficiently sensitive in young children. We hypothesised that ETI rapidly modifies the lungs' metabolism, resulting in changes in breath composition.
Methods: Eleven children with CF were enrolled in a longitudinal pilot study at the paediatric Necker hospital.
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