The link between environment and health has been well established, as has the need to develop strategies to manage the environment to protect health. The response of many governments to the emergence of environment as a leading concern of public health policy has been to fragment environment and health functions across many agencies, without effective coordination or communication systems, resulting in poor planning frameworks. There is a deepening awareness by many in government and international agencies of the need to develop 'national environmental health plans' (NEHAPS) to build and integrate environment and health policy and practice. To date, however, experience in the development of these and similar plans indicates that prescriptive 'top-down' approaches to plan development may yield limited success. This paper describes an ongoing project in Vietnam to develop a process for a national environmental health plan that provides a strong link between policies and practice, and utilizes a learning model for plan development. As environmental health is a new concept in Vietnam, significant attention has been given to the development of both national and local visions. The lessons learnt to date indicate that the use of a learning framework may provide a strong basis for the emergence of environmental health policy and its management. Facilitation of this process has required the use of a variety of change management tools and has placed an emphasis on using them in culturally sensitive ways. It is hoped that the emerging model, which gives environmental health its first expression at both national and provincial levels, will be of value to others undertaking similar policy and planning initiatives.
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http://dx.doi.org/10.1093/heapro/17.4.373 | DOI Listing |
Am J Cancer Res
December 2024
Department of Thoracic Surgery, Akita University Graduate School of Medicine Akita 010-8543, Japan.
Poor oral health is an independent risk factor for upper-aerodigestive tract cancers, including esophageal squamous cell carcinoma (ESCC); thus, good oral health may reduce the risk of ESCC. We previously reported that high expression of Toll-like receptor (TLR) 6, which recognizes peptidoglycan (PGN) from Gram-positive bacteria correlates with a good prognosis after esophagectomy for ESCC. Most beneficial bacteria in the mouth are Gram-positive.
View Article and Find Full Text PDFMicrobial eukaryotes (aka protists) are known for their important roles in nutrient cycling across different ecosystems. However, the composition and function of protist-associated microbiomes remains largely elusive. Here, we employ cultivation-independent single-cell isolation and genome-resolved metagenomics to provide detailed insights into underexplored microbiomes and viromes of over 100 currently uncultivable ciliates and amoebae isolated from diverse environments.
View Article and Find Full Text PDFMicrobial communities play a central role in transforming environments across Earth, driving both physical and chemical changes. By harnessing these capabilities, synthetic microbial communities, assembled from the bottom up, offer valuable insights into the mechanisms that govern community functions. These communities can also be tailored to produce desired outcomes, such as the synthesis of health-related metabolites or nitrogen fixation to improve plant productivity.
View Article and Find Full Text PDFBrain Behav Immun Health
February 2025
Department of Psychiatry, University of Campania "L. Vanvitelli", 80138, Naples, Italy.
Severe mental disorders are multi-dimensional constructs, resulting from the interaction of genetic, biological, psychosocial, and environmental factors. Among the latter, pollution and climate change are frequently being considered in the etiopathogenesis of severe mental disorders. This systematic review aims to investigate the biological mechanisms behind the relationship between environmental pollutants, climate change, and mental disorders.
View Article and Find Full Text PDFCurr Res Toxicol
December 2024
National Institute of Environmental Health Sciences, Division of Translational Toxicology, National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, P.O. Box 12233, Research Triangle Park, NC 27709, USA.
Mechanistically based non-animal methods for assessing skin sensitization hazard have been developed, but are not considered sufficient, individually, to conclusively define the skin sensitization potential or potency of a chemical. This resulted in the development of defined approaches (DAs), as documented in OECD TG 497, for combining information sources in a prescriptive manner to provide a determination of risk or potency. However, there are currently no DAs within OECD TG 497 that can derive a point of departure (POD) for risk assessment.
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