Paraplegia from ischemic injury of the spinal cord and renal failure from inadequate perfusion of the kidneys may occur from aortic cross-clamping during repair of traumatic thoracic aortic injuries. After Institutional Review Board approval, we retrospectively reviewed the charts of 26 patients surgically treated for traumatic transection of the descending thoracic aorta during a 14 year period (1987-2001), using centrifugal pump (Sarns) support for distal aortic perfusion. The study group comprised 19 males and 7 females, whose ages ranged from 15 to 69 years. For all but 1 patient, who fell from a flagpole, the injuries were incurred in motor vehicle accidents. Aortic cross-clamp time lasted between 5 to 78 min (median = 40 min). Mean arterial pressure ranged from 50 to 80 mm Hg (median = 70 mm Hg). All patients survived operation without developing paraplegia or renal failure. Distal centrifugal pump perfusion during repair of traumatic injury of the descending thoracic aorta is a valuable adjunct during surgical treatment and aids in preservation of spinal cord and renal function.
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http://dx.doi.org/10.1046/j.1525-1594.2002.07129.x | DOI Listing |
Int Heart J
December 2024
Department of Cardiovascular Surgery, The Second Hospital of Jilin University.
This study aimed to summarize our experience using a systematic approach to reduce blood transfusions in acute type A aortic dissection (ATAAD) surgery.From August 2016 to June 2020, 326 patients underwent ATAAD surgery in our center employing a systematic approach, which primarily included the following: Liu's aortic root repair technique, Liu's aortic arch inclusion technique with a frozen elephant trunk, moderate-to-mild hypothermia circulatory arrest, and application of centrifugal pump in cardiopulmonary bypass circuit. Patients were divided into two groups based on whether they had blood product transfusion during their hospital stay: transfusion group and transfusion-free group.
View Article and Find Full Text PDFNutrients
November 2024
Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, MI 49503, USA.
Background/objectives: Multiple independent variables were analyzed to determine total nutritional intake (caloric and protein), while reviewing vasoactive inotrope scores (VISs).
Methods: Retrospective data were collected for nutritional intake (N = 64), daily VISs, extracorporeal membrane oxygenation (ECMO) complications, delays in nutritional intake (>48 h), reason for delay, and interruptions in nutrition support.
Results: VISs and ECMO characteristics analyzed by box-whisker plots demonstrated that ECMO complications prior to 24 h, cardiac arrest 24 h prior to ECMO, pediatric ECMO patients, venoarterial ECMO type, having a cardiac ECMO indication, and ECMO centrifugal pump had higher VISs.
Bioengineering (Basel)
November 2024
Biomedical Research Center, Qatar University, Doha 2713, Qatar.
A comprehensive analysis of in vitro pumps used in cardiovascular research is provided in this review, with a focus on the characteristics of generated flows and principles of flow generations. The cardiovascular system, vital for nutrient circulation and waste removal, generates complex hemodynamics critical for endothelial cell function. Cardiovascular diseases (CVDs) could be caused by the disturbances in these flows, including aneurysms, atherosclerosis, and heart defects.
View Article and Find Full Text PDFArtif Organs
November 2024
Department of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Pitié Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne University, Paris, France.
Background: An innovative solution has been recently proposed for the treatment of heart failure with preserved ejection fraction (HFpEF), using a centrifugal mechanical circulatory support (MCS) device. We sought firstly to assess the hemocompatibility of the proposed device. HFpEF treatment requires the blood pump to operate at low blood flow rate (0.
View Article and Find Full Text PDFJ Biomech Eng
February 2025
Arts et Métiers Institute of Technology, CNAM, LIFSE, Paris F-75013, France.
Blood pumps, critical components in ventricular assist devices and extracorporeal membrane oxygenation systems, are primarily evaluated based on their ability to minimize blood damage through optimized design. Despite extensive research, the impact of impeller blade thickness and the proximity of rotating and stationary surfaces remains insufficiently explored. This study presents a comprehensive analysis, combining experimentally validated numerical simulations with an advanced Lagrangian approach, to compare the hemodynamic and hemolytic performance of three centrifugal pumps.
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