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Tumor microenvironment-responsive hyperbranched polymers for controlled drug delivery.
J Pharm Anal
December 2024
Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.
Hyperbranched polymers (HBPs) have drawn great interest in the biomedical field on account of their special morphology, low viscosity, self-regulation, and facile preparation methods. Moreover, their large intramolecular cavities, high biocompatibility, biodegradability, and targeting properties render them very suitable for anti-tumor drug delivery. Recently, exploiting the specific characteristics of the tumor microenvironment, a range of multifunctional HBPs responsive to the tumor microenvironment have emerged.
View Article and Find Full Text PDFEffect of Soaking Treatments in Acid and Salt Solutions on Physicochemical, Structural, Thermal and Rheological Properties of Porang ( Blume) Flour.
Food Technol Biotechnol
December 2024
Research Center for Appropriate Technology-National Research and Innovation Agency Jl. K.S. Tubun No. 5 Subang 41213, West Java, Indonesia.
Research Background: Porang ( Blume) contains a high amount of starch, glucomannan and Ca-oxalate. Soaking porang tuber in acid (citric acid) and salt (sodium chloride) solutions affects the Ca-oxalate content, functional, rheological and thermal properties of porang flour. The aim of this study is to thoroughly investigate the effect of soaking treatments in acid and salt solutions at different temperatures on the physicochemical, rheological and thermal properties, functional groups, molecular mass and morphology of porang flour.
View Article and Find Full Text PDFActivatable red/near-infrared aqueous organic phosphorescence probes for improved time-resolved bioimaging.
Natl Sci Rev
February 2025
Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.
Organic red/near-infrared (NIR) room-temperature phosphorescence (RTP) holds significant potential for autofluorescence-free bioimaging and biosensing due to its prolonged persistent luminescence and exceptional penetrability. However, achieving activatable red/NIR organic RTP probes with tunable emission in aqueous solution remains a formidable challenge. Here we report on aqueous organic RTP probes with red/NIR phosphorescence intensity and lifetime amplification.
View Article and Find Full Text PDFResearch into the Impact of Seawater Ionic Composition on the Rheological Characteristics of a Cationic Guar Gum-Based Fracturing Fluid.
ACS Omega
January 2025
School of Petroleum Engineering, Xi 'an Shiyou University, No. 18, East Section of Electronic second Road, Yanta District, Xi'an, Shaanxi 710054, China.
This study examined the effects of salt content and salt type on the properties of the hydroxypropyl guar gum fracturing fluid. In this study, we conducted a thorough analysis of the impact that various ions in seawater have on the performance of fracturing fluids. We identified the cross-linked polymer that performs optimally at a specific concentration of the binding agent.
View Article and Find Full Text PDFEnhancing the Rheological and Filtration Performance of Water-Based Drilling Fluids Using Silane-Coated Aluminum Oxide NPs.
ACS Omega
January 2025
Department of Metallurgy & Materials Engineering, Mehran University of Engineering and Technology, Jamshoro, Sindh 76062, Pakistan.
For optimizing the drilling efficiency, nanoparticles (NPs) specifically nanometal oxides have been used in water-based drilling fluids (WBDF). Nano metal oxides improve the rheological and filtration characteristics of the WBDF. However, dispersion instability among pristine nano metals shrinks the performance of the nanometal oxides due to high surface energy.
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